Differential associations of systolic and diastolic time rate of blood pressure variation with carotid atherosclerosis and plaque echogenicity
Artikel i vetenskaplig tidskrift, 2017

In the current study, the authors sought to assess whether the time rate of systolic and diastolic blood pressure variation is associated with advanced subclinical stages of carotid atherosclerosis and plaque echogenicity assessed by gray scale median. The authors recruited 237 consecutive patients with normotension and hypertension who underwent 24-hour ambulatory blood pressure monitoring and carotid artery ultrasonography. There was an independent association between low 24-hour systolic time rate and increased echogenicity of carotid plaques (adjusted odds ratio for highest vs lower tertiles of gray scale median, 0.470; 95% confidence interval, 0.245-0.902 [P = .023]). Moreover, increased nighttime diastolic time rate independently correlated with the presence (adjusted odds ratio, 1.328; P = .015) and number of carotid plaques (adjusted odds ratio, 1.410; P = .003). These results indicate differential associations of the systolic and diastolic components of time rate of blood pressure variation with the presence, extent, and composition of carotid plaques and suggest that when blood pressure variation is assessed, both components should be considered.

stroke

Cardiovascular System & Cardiology

risk

society

hypertensive patients

guidelines

european lacidipine

disease

variability

intima-media thickness

Författare

A. Kolyviras

University of Athens Medical School

E. Manios

University of Athens Medical School

G. Georgiopoulos

University of Athens Medical School

F. Michas

University of Athens Medical School

Tomas Gustavsson

Chalmers, Signaler och system

E. Papadopoulou

University of Athens Medical School

L. Ageliki

University of Athens Medical School

J. Kanakakis

University of Athens Medical School

C. Papamichael

University of Athens Medical School

G. Stergiou

University of Athens

N. Zakopoulos

University of Athens Medical School

K. Stamatelopoulos

University of Athens Medical School

Journal of Clinical Hypertension

1524-6175 (ISSN)

Vol. 19 11 1070-1077

Styrkeområden

Building Futures

Livsvetenskaper och teknik

Ämneskategorier

Klinisk medicin

Annan medicin och hälsovetenskap

Kemi

Fundament

Grundläggande vetenskaper

DOI

10.1111/jch.13070

Mer information

Skapat

2017-12-13