The pan-genome of Saccharomyces cerevisiae
Artikel i vetenskaplig tidskrift, 2019

Understanding genotype-phenotype relationship is fundamental in biology. With the benefit from next-generation sequencing and high-throughput phenotyping methodologies, there have been generated much genome and phenome data for Saccharomyces cerevisiae. This makes it an excellent model system to understand the genotype-phenotype relationship. In this paper, we presented the reconstruction and application of the yeast pan-genome in resolving genotype-phenotype relationship by a machine learning-assisted approach.

pan-genome

Saccharomyces cerevisiae

genotype–phenotype relationship

machine learning

Författare

Gang Li

Chalmers, Biologi och bioteknik, Systembiologi

Boyang Ji

Chalmers, Biologi och bioteknik, Systembiologi

Jens B Nielsen

Chalmers, Biologi och bioteknik, Systembiologi

Danmarks Tekniske Universitet (DTU)

FEMS Yeast Research

1567-1356 (ISSN) 1567-1364 (eISSN)

Vol. 19 7

Ämneskategorier

Transportteknik och logistik

Bioinformatik (beräkningsbiologi)

Bioinformatik och systembiologi

DOI

10.1093/femsyr/foz064

PubMed

31584649

Mer information

Senast uppdaterat

2019-11-12