The pan-genome of Saccharomyces cerevisiae
Journal article, 2019

Understanding genotype-phenotype relationship is fundamental in biology. With the benefit from next-generation sequencing and high-throughput phenotyping methodologies, there have been generated much genome and phenome data for Saccharomyces cerevisiae. This makes it an excellent model system to understand the genotype-phenotype relationship. In this paper, we presented the reconstruction and application of the yeast pan-genome in resolving genotype-phenotype relationship by a machine learning-assisted approach.

machine learning

genotype–phenotype relationship

pan-genome

Saccharomyces cerevisiae

Author

Gang Li

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

Boyang Ji

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

Jens B Nielsen

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

Technical University of Denmark (DTU)

FEMS Yeast Research

1567-1356 (ISSN) 1567-1364 (eISSN)

Vol. 19 7 foz064

Subject Categories

Transport Systems and Logistics

Microbiology

Bioinformatics (Computational Biology)

Bioinformatics and Systems Biology

DOI

10.1093/femsyr/foz064

PubMed

31584649

Related datasets

The pan-genome of Saccharomyces cerevisiae [dataset]

DOI: 10.5281/zenodo.2591939

More information

Latest update

9/22/2023