Calculation of decision threshold and detection limit in radiometric measurements using a Monte Carlo Method
Artikel i vetenskaplig tidskrift, 2020

Calculation of the decision threshold and detection limit of a measurement, or measurement method, are crucial in order to decide if an analyte is present or not and with what confidence it can be quantified. That decision is important in view of possible actions if something would be detected. In this work, a method for calculating these limits using a Monte Carlo method is presented. In the Monte Carlo method any a priori distribution (e.g. normal distribution, rectangular distribution, triangular distribution) of an input quantity can be selected. Differences between the Monte Carlo calculated characteristic limits and the ones calculated according to ISO 11929:2010 is presented. Moreover, suggestions how to calculate the detection limit when it can not be calculated according to the ISO 11929:2010 are given.

MDA

Decision threshold

Detection limit

Minimum detectable activity

Monte Carlo

Författare

Henrik Ramebäck

Totalförsvarets forskningsinstitut (FOI)

Chalmers, Kemi och kemiteknik

L. Persson

Totalförsvarets forskningsinstitut (FOI)

Christian Ekberg

Chalmers, Kemi och kemiteknik, Energi och material

P. Lindgren

Totalförsvarets forskningsinstitut (FOI)

M. Bruggeman

Belgian Nuclear Research Center

Applied Radiation and Isotopes

0969-8043 (ISSN)

Vol. 156 108949

Ämneskategorier

Subatomär fysik

Biofysik

Radiologi och bildbehandling

DOI

10.1016/j.apradiso.2019.108949

Mer information

Senast uppdaterat

2019-11-15