Graphene-based biosensors for the detection of prostate cancer protein biomarkers: a review
Reviewartikel, 2019
Prostate cancer (PC) is the sixth most common cancer type in the world, which causes approximately 10% of total cancer fatalities. The detection of protein biomarkers in body fluids is the key topic for the diagnosis and prognosis of PC. Highly sensitive screening of PC is the most effective approach for reducing mortality. Thus, there are a growing number of literature that recognizes the importance of new technologies for early diagnosis of PC. Graphene is playing an important role in the biosensor field with remarkable physical, optical, electrochemical and magnetic properties. Many recent studies demonstrated the potential of graphene materials for sensitive detection of protein biomarkers. In this review, the graphene-based biosensors toward PC analysis are mainly discussed in two groups: Firstly, novel biosensor interfaces were constructed through the modification of graphene materials onto sensor surfaces. Secondly, ingenious signal amplification strategies were developed using graphene materials as catalysts or carriers. Graphene-based biosensors have exhibited remarkable performance with high sensitivities, wide detection ranges, and long-term stabilities.
Biosensor
Graphene
Prostate cancer
Protein biomarker
Författare
Li Xu
Chalmers, Biologi och bioteknik, Systembiologi
Shanghai Inst Measurement & Testing Technol
Yanli Wen
Shanghai Inst Measurement & Testing Technol
Santosh Pandit
Chalmers, Biologi och bioteknik, Systembiologi
Venkata Raghavendra Subrahmanya Sar Mokkapati
Chalmers, Kemi och kemiteknik, Energi och material, Oorganisk miljökemi 2
Ivan Mijakovic
Chalmers, Biologi och bioteknik, Systembiologi
Novo Nordisk Foundation Center for Biosustainability
Yan Li
Shanghai Inst Measurement & Testing Technol
Min Ding
Shanghai Inst Measurement & Testing Technol
Shuzhen Ren
Shanghai Inst Measurement & Testing Technol
Wen Li
Shanghai Inst Measurement & Testing Technol
Gang Liu
Shanghai Inst Measurement & Testing Technol
BMC CHEMISTRY
2661-801X (eISSN)
Vol. 13 1 UNSP 112Ämneskategorier
Analytisk kemi
Urologi och njurmedicin
Cancer och onkologi
DOI
10.1186/s13065-019-0611-x
PubMed
31508598