Broadband prosthetic interfaces: Combining nerve transfers and implantable multichannel EMG technology to decode spinal motor neuron activity
Artikel i vetenskaplig tidskrift, 2017

Modern robotic hands/upper limbs may replace multiple degrees of freedom of extremity function. However, their intuitive use requires a high number of control signals, which current man-machine interfaces do not provide. Here, we discuss a broadband control interface that combines targeted muscle reinnervation, implantable multichannel electromyographic sensors, and advanced decoding to address the increasing capabilities of modern robotic limbs. With targeted muscle reinnervation, nerves that have lost their targets due to an amputation are surgically transferred to residual stump muscles to increase the number of intuitive prosthetic control signals. This surgery re-establishes a nerve-muscle connection that is used for sensing nerve activity with myoelectric interfaces. Moreover, the nerve transfer determines neurophysiological effects, such as muscular hyper-reinnervation and cortical reafferentation that can be exploited by the myoelectric interface. Modern implantable multichannel EMG sensors provide signals from which it is possible to disentangle the behavior of single motor neurons. Recent studies have shown that the neural drive to muscles can be decoded from these signals and thereby the user's intention can be reliably estimated. By combining these concepts in chronic implants and embedded electronics, we believe that it is in principle possible to establish a broadband man-machine interface, with specific applications in prosthesis control. This perspective illustrates this concept, based on combining advanced surgical techniques with recording hardware and processing algorithms. Here we describe the scientific evidence for this concept, current state of investigations, challenges, and alternative approaches to improve current prosthetic interfaces.

Författare

Konstantin D. Bergmeister

Universität Heidelberg

Medizinische Universität Wien

Ivan Vujaklija

Imperial College London

Silvia Muceli

Universitätsmedizin Göttingen

Agnes Sturma

FH Technikum Wien

Medizinische Universität Wien

Laura A. Hruby

Medizinische Universität Wien

Cosima Prahm

Medizinische Universität Wien

Otto Riedl

Medizinische Universität Wien

Stefan Salminger

Medizinische Universität Wien

Krisztina Manzano-Szalai

Medizinische Universität Wien

Martin Aman

Medizinische Universität Wien

Michael-Friedrich Russold

Otto Bock Healthcare Products GmbH

Christian Hofer

Medizinische Universität Wien

Otto Bock Healthcare Products GmbH

Jose Principe

University of Florida

Dario Farina

Imperial College London

Oskar C. Aszmann

Medizinische Universität Wien

Frontiers in Neuroscience

1662-4548 (ISSN)

Vol. 11 1-8 421

Ämneskategorier

Psykologi (exklusive tillämpad psykologi)

Neurovetenskaper

DOI

10.3389/fnins.2017.00421

Mer information

Senast uppdaterat

2021-04-21