Sustained and triggered release by microencapsulation
In this work, microencapsulation was used as a means of controlling the rate at which a model hydrophobic substance was released in two different ways. A slow sustained release microparticle system with a complete release over a period of weeks was developed. These microcapsules were also incorporated into cellulose fibers, to produce a nonwoven material possessing controlled release properties. As a complement to this, a fast triggered release system was developed where a significant release could be seen within minutes of the trigger event.
Through a combination of these two types of controlled release, a hypothetical release profile could be tailored to fit specific applications. The triggered release microparticles could initially increase the antimicrobial concentration above a certain effective concentration, and the sustained release microparticles would maintain the concentration above the effective concentration for a prolonged time. The use in a nonwoven fiber material was illustrated in this work, although use in e.g. continuous fibers or painted coatings could also easily be conceived.
Chalmers, Kemi och kemiteknik, Tillämpad kemi, Lars Evenäs Group
Hanna Ulmefors, Ting Yang Nilsson, Viktor Eriksson, Gustav Eriksson, Lars Evenäs, and Markus Andersson Trojer. Solution-spinning of a collection of micro- and nanocarrier-functionalized polysaccharide fibers
Viktor Eriksson, Jules Mistral, Ting Yang Nilsson, Markus Andersson Trojer, and Lars Evenäs. Microencapsulation for controlled release of model active substances from cellulose nonwovens
Formulation of polyphthalaldehyde microcapsules for immediate UV-light triggered release
Journal of Colloid and Interface Science,; Vol. 579(2020)p. 645-653
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