A Monte Carlo method for calculation of the characteristic limits decision threshold and detection limit in low-level radioactivity measurements
Artikel i vetenskaplig tidskrift, 2021

In this study, calculation of decision threshold and detection limit expressed in counts for low-level radioactivity measurements were evaluated and compared to a Monte Carlo method for the case of paired Poisson-distributed observations, i.e. for discrete variables. The calculated characteristic limits obtained from Monte Carlo calculations were compared with analytical expressions given in literature. The results in this study show that the equations given by Currie are in good agreement with the results from the Monte Carlo calculations simulating nuclear counting applications with a low number of observed counts. An exception is observed for a background corresponding to zero counts. This study also shows that at a low number of counts, the specific boundary conditions of the interval that represents counts corresponding to the presence of the analyte (>or ≥), have an impact on the false positives and negatives rates as defined by the parameters α and β.

Decision threshold

Detection limit

Low count rate

Monte Carlo calculation

Currie

Författare

Henrik Ramebäck

Totalförsvarets forskningsinstitut (FOI)

L. Persson

Totalförsvarets forskningsinstitut (FOI)

Christian Ekberg

Chalmers, Kemi och kemiteknik, Energi och material

Anna Vesterlund

Totalförsvarets forskningsinstitut (FOI)

M. Bruggeman

Belgian Nuclear Research Center (SCK CEN)

Applied Radiation and Isotopes

0969-8043 (ISSN)

Vol. 178 109959

Ämneskategorier

Biofysik

Sannolikhetsteori och statistik

Radiologi och bildbehandling

DOI

10.1016/j.apradiso.2021.109959

PubMed

34601271

Mer information

Senast uppdaterat

2021-10-15