How deep can we decipher protein evolution with deep learning models
Övrig text i vetenskaplig tidskrift, 2024

Evolutionary-based machine learning models have emerged as a fascinating approach to mapping the landscape for protein evolution. Lian et al. demonstrated that evolution-based deep generative models, specifically variational autoencoders, can organize SH3 homologs in a hierarchical latent space, effectively distinguishing the specific Sho1(SH3) domains.

Författare

Xiaozhi Fu

Chalmers, Life sciences, Systembiologi

Patterns

26663899 (eISSN)

Vol. 5 8 101043

Ämneskategorier

Biologiska vetenskaper

DOI

10.1016/j.patter.2024.101043

Mer information

Senast uppdaterat

2024-11-08