Reframing the role of the objective function in its proper context for metabolic network modeling
Övrig text i vetenskaplig tidskrift, 2025
The “objective function” is a core concept in metabolic network modeling. Its use has enabled the analysis of large data to drive deeper understanding of cellular metabolism. This commentary reframes how the objective function is discussed to enhance its value and clarify misunderstandings in metabolic network modeling.
Författare
Mohammad Mazharul Islam
University of Virginia
William Shao
University of Virginia
Mariska Batavia
University of Virginia
Roseanne M. Ford
University of Virginia
B. O. Palsson
University of California
Jens B Nielsen
Chalmers, Life sciences, Systembiologi
Costas D. Maranas
Penn State College of Engineering
Sang Yup Lee
Korea Advanced Institute of Science and Technology (KAIST)
J. A. Papin
University of Virginia
Cell Systems
24054712 (ISSN) 24054720 (eISSN)
Vol. 16 6 101298Ämneskategorier (SSIF 2025)
Cellbiologi
DOI
10.1016/j.cels.2025.101298