Conformation of 1-aryl-2-aryloxy-1-propanols: threo-1-(4-hydroxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)-1-propanol
Artikel i vetenskaplig tidskrift, 2008

The title compound, C17H20O5, (I), is structurally related to naturally occurring 1-aryl-2-aryloxy-1-propanols. Such compounds are of interest as lignin models, and neolignans of this type have been detected in a large number of plants. In the crystal structure of (I), the molecules adopt a conformation in which the aryl groups are far apart from each other. The O(aryloxy)-C-C-C(aryl) torsion angle is 177.76(14)°. The conformation is compared with those of other compounds (neolignans and lignin model compounds) of the 1-aryl-2-aryloxy-1-propanol type (including some acetate derivatives). The comparison shows that in all the examined compounds the above-mentioned torsion angle is close to 180°, and the distance between the centers of the aromatic rings approaches the maximum achievable in most of the compounds. The hydrogen-bonding pattern of (I) is discussed in terms of graph-set theory.

lignin model


X-ray strusture determination


Vratislav Langer

Chalmers, Kemi- och bioteknik, Oorganisk miljökemi

Shiming Li

Chalmers, Kemi- och bioteknik, Skogsindustriell kemiteknik

Knut Lundquist

Chalmers, Kemi- och bioteknik, Skogsindustriell kemiteknik

Acta Crystallographica Section C: Crystal Structure Communications

0108-2701 (ISSN) 1600-5759 (eISSN)

Vol. C64 10 o558-o560



Organisk kemi



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