Development of thermostable enzyme cocktails
Research Project , 2017 – 2021

The goal of this project is to significantly improve hydrolysis of plant biomass (lignocellulose). Enzymatic hydrolysis is regarded as more sustainable than thermochemical alternatives, but is still expensive and needs improvement. The improvement will here be made by developing and producing heat tolerant enzymes with multiple catalytic domains. Typically, enzymes have one catalytic domain, but in certain organisms ‘multicatalytic’ enzymes are common, and have been shown to outcompete commercial variants. These bacteria we study live in extreme environments such as hot springs, making their enzymes highly stable and active at these temperatures (>70°), and enable higher hydrolysis temperatures than in typical industrial processes. The high temperatures lead to higher hydrolysis rates as well as reduced risks of microbial contamination.

Participants

Johan Larsbrink (contact)

Forskarassistent vid Chalmers, Biology and Biological Engineering, Industrial Biotechnology

Daniel Krska

Doktorand vid Chalmers, Biology and Biological Engineering, Industrial Biotechnology

Funding

Swedish Energy Agency

Funding Chalmers participation during 2018–2019

Formas

Funding Chalmers participation during 2017–2020

Related Areas of Advance and Infrastructure

Sustainable development

Driving Forces

Energy

Areas of Advance

Life Science Engineering

Areas of Advance

More information

Latest update

2018-07-19