Study of proper placements of HEPA-filter units in order to prevent airborne contamination of autoclaves in aseptic production by using computional fluid dynamics
Magazine article, 2013

Autoclaves are common process equipment used in the pharmaceutical industry. This type of process equipment can cause temperature differences relative to ambient air. During unloading autoclaves used for aseptic production, entrainment of room air into the loading chamers may occur creating contamination risks. To minimize these risks, high-efficiency particulate air filter units with unidirectional flow (UDF) can be used to provide the chamber openings with clean air protection. This paper describes the use of computational fluid dynamics to simulate unloading of autoclaves used for aseptic production in meaning to improve the understanding of contamination risks of the autoclave chamber and present solutions of proper placement of HEPA-filters in order to protect the openings of autoclaves.

autoclaves

HEPA-filter

Author

Catinka Ullman

Chalmers, Energy and Environment, Building Services Engineering

Bengt Ljungqvist

Chalmers, Energy and Environment, Building Services Engineering

Berit Reinmüller

Chalmers, Energy and Environment, Building Services Engineering

Jenny Sahlén

Renhetsteknik

Vol. 2013 3 15-20

Driving Forces

Sustainable development

Areas of Advance

Building Futures (2010-2018)

Subject Categories

Other Medical and Health Sciences

More information

Created

10/6/2017