Study of proper placements of HEPA-filter units in order to prevent airborne contamination of autoclaves in aseptic production by using computional fluid dynamics
Artikel i övrig tidskrift, 2013

Autoclaves are common process equipment used in the pharmaceutical industry. This type of process equipment can cause temperature differences relative to ambient air. During unloading autoclaves used for aseptic production, entrainment of room air into the loading chamers may occur creating contamination risks. To minimize these risks, high-efficiency particulate air filter units with unidirectional flow (UDF) can be used to provide the chamber openings with clean air protection. This paper describes the use of computational fluid dynamics to simulate unloading of autoclaves used for aseptic production in meaning to improve the understanding of contamination risks of the autoclave chamber and present solutions of proper placement of HEPA-filters in order to protect the openings of autoclaves.




Catinka Ullmann

Chalmers, Energi och miljö, Installationsteknik

Bengt Ljungqvist

Chalmers, Energi och miljö, Installationsteknik

Berit Reinmüller

Chalmers, Energi och miljö, Installationsteknik

Jenny Sahlén


Vol. 2013 3 15-20


Hållbar utveckling


Building Futures (2010-2018)


Annan medicin och hälsovetenskap

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