Chromosome 3p loss of heterozygosity is associated with a unique metabolic network in clear cell renal carcinoma
Journal article, 2014
genome-scale metabolic modeling
HETEROGENEITY
MODEL
cancer metabolism
GROWTH
DRUG TARGETS
VHL
CANCER
HYPOXIA
GENE-EXPRESSION
NOVO PYRIMIDINE SYNTHESIS
systems biology
SET
renal cancer
Author
Francesco Gatto
Chalmers, Chemical and Biological Engineering, Life Sciences
Intawat Nookaew
Chalmers, Chemical and Biological Engineering, Life Sciences
Jens B Nielsen
Chalmers, Chemical and Biological Engineering, Life Sciences
Proceedings of the National Academy of Sciences of the United States of America
0027-8424 (ISSN) 1091-6490 (eISSN)
Vol. 111 9 E866-E875Infrastructure
C3SE (Chalmers Centre for Computational Science and Engineering)
Areas of Advance
Life Science Engineering (2010-2018)
Subject Categories
Chemical Sciences
Cancer and Oncology
DOI
10.1073/pnas.1319196111