Joint feedback analysis modeling of nonesterified fatty acids in obese zucker rats and normal sprague-dawley rats after different routes of administration of nicotinic acid
Journal article, 2014
Disease modeling
Monte carlo
Nonlinear regression
Pharmacodynamics
Sensitivity analysis
Nonesterified fatty acids (NEFAs)
Mathematical models
Feedback
Disease state
Author
Sofia Tapani
Joachim Almquist
Chalmers, Chemical and Biological Engineering, Life Sciences
Jacob Leander
University of Gothenburg
Chalmers, Mathematical Sciences, Mathematics
Christine Ahlström
Lambertus A. Peletier
Mats Jirstrand
Johan Gabrielsson
Journal of Pharmaceutical Sciences
0022-3549 (ISSN) 15206017 (eISSN)
Vol. 103 8 2571-2584Subject Categories
Mathematics
Bioinformatics and Systems Biology
Areas of Advance
Life Science Engineering (2010-2018)
DOI
10.1002/jps.24077