Joachim Almquist

Publications (28)
Projects (0)

Showing 28 publications

2022

Exposure-response modeling improves selection of radiation and radiosensitizer combinations

Tim Cardilin, Joachim Almquist, Mats Jirstrand et al

Journal of Pharmacokinetics and Pharmacodynamics. Vol. 49 (2), p. 167-178

Journal article

2020

NLMEModeling: A Wolfram Mathematica Package for Nonlinear Mixed Effects Modeling of Dynamical Systems

Jacob Leander, Joachim Almquist, Anna Johnning et al

Preprint

2019

Parameter Estimation for Nonlinear Mixed Effects Models Implemented in Mathematica

Jacob Leander, Joachim Almquist, Helga Kristín Ólafsdóttir et al

Conference poster

2019

Modeling long-term tumor growth and kill after combinations of radiation and radiosensitizing agents

Tim Cardilin, Joachim Almquist, Mats Jirstrand et al

Cancer Chemotherapy and Pharmacology. Vol. 83 (6), p. 1159-1173

Journal article

2018

Modeling of radiation therapy and radiosensitizing agents in tumor xenografts

Tim Cardilin, Joachim Almquist, Mats Jirstrand et al

Conference poster

2018

Overexpressing cell systems are a competitive option to primary adipocytes when predicting in vivo potency of dual GPR81/GPR109A agonists

Joachim Almquist, Daniel Hovdal, Christine Ahlström et al

European Journal of Pharmaceutical Sciences. Vol. 114, p. 155-165

Journal article

2018

Model-based evaluation of radiation and radiosensitizing agents in oncology

Tim Cardilin, Joachim Almquist, Mats Jirstrand et al

CPT: Pharmacometrics and Systems Pharmacology. Vol. 7 (1), p. 51-58

Journal article

2018

Evaluation and translation of combination therapies in oncology – A quantitative approach

Tim Cardilin, Joachim Almquist, Mats Jirstrand et al

European Journal of Pharmacology. Vol. 834, p. 327-336

Journal article

2018

Exact Gradients Improve Parameter Estimation in Nonlinear Mixed Effects Models with Stochastic Dynamics

Helga Kristín Ólafsdóttir, Jacob Leander, Joachim Almquist et al

AAPS Journal. Vol. 20 (5)

Journal article

2017

Hemostatic effects of the ticagrelor antidote MEDI2452 in pigs treated with ticagrelor on a background of aspirin

S. Pehrsson, K. J. Johansson, A. Janefeldt et al

Journal of Thrombosis and Haemostasis. Vol. 15 (6), p. 1213-1222

Journal article

2017

Multiple computational modeling approaches for prediction of wound healing dynamics following pharmacologic intervention

S. M. Rikard, Joachim Almquist, A. Lundahl et al

Biomedical Engineering Society (BMES) annual meeting, Phoenix, AZ, USA, 11-14 October 2017

Paper in proceeding

2017

Modeling of free fatty acid dynamics: insulin and nicotinic acid resistance under acute and chronic treatments

R. Andersson, T. Kroon, Joachim Almquist et al

Journal of Pharmacokinetics and Pharmacodynamics. Vol. 44 (3), p. 203-222

Journal article

2017

Kinetic Models in Life Science — Contributions to Methods and Applications

Joachim Almquist

Doctoral thesis

2017

Exact Gradients Improve Parameter Estimation in Nonlinear Mixed Effects Models with Stochastic Dynamics

Helga Kristin Olafsdottir, Jacob Leander, Joachim Almquist et al

Conference poster

2017

Tumor Static Concentration Curves in Combination Therapy

Tim Cardilin, Joachim E Almqvist, Mats Jirstrand et al

AAPS Journal. Vol. 19 (2), p. 456-467

Journal article

2016

Extending the Tumor Static Concentration curve to average doses - a combination therapy example using radiation therapy

Tim Cardilin, Astrid Zimmermann, Mats Jirstrand et al

Proceedings of the 25th Annual meeting of the Population Approach Group in Europe, PAGE2016

Conference poster

2016

Unraveling the Pharmacokinetic Interaction of Ticagrelor and MEDI2452 (Ticagrelor Antidote) by Mathematical Modeling

Joachim Almquist, M. Penney, S. Pehrsson et al

CPT: Pharmacometrics and Systems Pharmacology. Vol. 5 (6), p. 313-323

Journal article

2015

Using sensitivity equations for computing gradients of the FOCE and FOCEI approximations to the population likelihood

Joachim Almquist, Jacob Leander, Mats Jirstrand

Journal of Pharmacokinetics and Pharmacodynamics. Vol. 42 (3), p. 191-209

Journal article

2015

Mixed Effects Modeling Using Stochastic Differential Equations: Illustrated by Pharmacokinetic Data of Nicotinic Acid in Obese Zucker Rats

Jacob Leander, Joachim Almquist, Christine Ahlström et al

AAPS Journal. Vol. 17 (3), p. 586-596

Journal article

2015

Sensitivity Equations Provide More Robust Gradients and Faster Computation of the FOCE Approximation to the Population Likelihood

Joachim Almquist, Jacob Leander, Mats Jirstrand

Conference poster

2015

A nonlinear mixed effects approach for modeling the cell-to-cell variability of Mig1 dynamics in yeast.

Joachim Almquist, Loubna Bendrioua, Caroline B. Adiels et al

PLoS ONE. Vol. 10 (4), p. e0124050-

Journal article

2014

Joint feedback analysis modeling of nonesterified fatty acids in obese zucker rats and normal sprague-dawley rats after different routes of administration of nicotinic acid

Sofia Tapani, Joachim Almquist, Jacob Leander et al

Journal of Pharmaceutical Sciences. Vol. 103 (8), p. 2571-2584

Journal article

2014

Yeast AMP-activated protein kinase monitors glucose concentration changes and absolute glucose levels

Loubna Bendrioua, Maria Smedh, Joachim Almquist et al

Journal of Biological Chemistry. Vol. 289 (18), p. 12863-12875

Journal article

2014

Mixed-effects modeling using stochastic differential equations - Applications to pharmacokinetic modeling

Jacob Leander, Joachim Almquist, Christine Ahlström et al

Population Approach Group Europe (PAGE) 2014

Conference poster

2014

Bridging the gaps in systems biology

Marija Cvijovic, Joachim Almquist, Jonas Hagmar et al

Molecular Genetics and Genomics. Vol. 289 (5), p. 727-734

Review article

2014

Kinetic models in industrial biotechnology - Improving cell factory performance

Joachim Almquist, Marija Cvijovic, V. Hatzimanikatis et al

Metabolic Engineering. Vol. 24, p. 38-60

Review article

2010

A Kinetic Model of the Monocarboxylate Transporter MCT1 and its Interaction with Carbonic Anhydrase II

Joachim E Almqvist, Patrick Lang, Dieter Prätzel-Wolters et al

Journal of Computer Science and Systems Biology. Vol. 3 (5), p. 107-116

Journal article

2010

Modeling the Effect of Kv1.5 Block on the Canine Action Potential

Joachim E Almqvist, Mikael Wallman, Ingemar Jacobson et al

Biophysical Journal. Vol. 99 (9), p. 2726-2736

Journal article

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