Tumor Static Concentration Curves in Combination Therapy
Journal article, 2017
mixture dynamics
tumor xenograft
oncology
model-based drug development
pharmacokinetic/pharmacodynamic modeling
Author
Tim Cardilin
University of Gothenburg
Chalmers, Mathematical Sciences, Mathematics
Joachim E Almqvist
Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology
Mats Jirstrand
Fraunhofer-Chalmers Centre
A. Sostelly
Merck KGaA
F. Hoffmann-La Roche AG
C. Amendt
Merck KGaA
S. El Bawab
Merck KGaA
Johan Gabrielsson
Swedish University of Agricultural Sciences (SLU)
AAPS Journal
1550-7416 (eISSN)
Vol. 19 2 456-467Subject Categories
Pharmaceutical Sciences
Computational Mathematics
Bioinformatics (Computational Biology)
Areas of Advance
Life Science Engineering (2010-2018)
DOI
10.1208/s12248-016-9991-1