Graphene Oxide and Lipid Membranes: Size-Dependent Interactions
Journal article, 2016

We have investigated the interaction of graphene oxide (GO) sheets with supported lipid membranes with focus on how the interaction depends on GO sheet size (three samples in the range of 90-5000 nm) and how it differs between small and large liposomes. The layer by-layer assembly of these materials into multilamellar structures, as discovered in our previous research, is now further explored. The interaction processes were monitored by two complementary, real time, surface-sensitive analytical techniques: quartz crystal microbalance with dissipation monitoring (QCM-D, electroacoustic sensing) and indirect nanoplasmonic sensing (INPS, optical sensing). The results show that the sizes of each of the two components, graphene oxide and liposomes, are important parameters affecting the resulting multilayer structures. Spontaneous liposome rupture onto graphene oxide is obtained for large lateral dimensions of the graphene oxide sheets.

vesicle adsorption

rupture

Chemistry

driven

kinetics

drugs

nanomaterials

delivery

Materials Science

bilayers

qcm-d

quartz-crystal microbalance

Author

Rickard Frost

Chalmers, Energy and Environment, Environmental Systems Analysis

Sofia Svedhem

Chalmers, Physics, Biological Physics

Christoph Langhammer

Chalmers, Physics, Chemical Physics

Bengt Herbert Kasemo

University of Gothenburg

Langmuir

07437463 (ISSN) 15205827 (eISSN)

Vol. 32 11 2708-2717

Subject Categories

Materials Chemistry

DOI

10.1021/acs.langmuir.5b03239

More information

Created

10/7/2017