Sofia Svedhem

Forskare at Department of Physics

Research focus: Model systems addressing nanoparticle interactions at biological interfaces/barriers.

Source: chalmers.se

Projects

2009–2014

NanoSphere: Centre for interaction and risk studies in Nano-Bio-Geo-Sociotechno-sphere interfaces

Sverker Molander Department of Energy and Environment, Environmental Systems Analysis
Sofia Svedhem Department of Applied Physics, Biological Physics
Eva Olsson Department of Applied Physics, Eva Olsson Group
Martin Andersson Department of Chemical and Biological Engineering, Applied Surface Chemistry
Rickard Frost Department of Energy and Environment, Environmental Systems Analysis
Bengt Herbert Kasemo Department of Applied Physics, Chemical Physics
Rickard Arvidsson Department of Energy and Environment, Environmental Systems Analysis
Formas

There might be more projects where Sofia Svedhem participates, but you have to be logged in as a Chalmers employee to see them.

Publications

2017

Asymmetric cationic liposomes designed for heat-activated association with cells

Yujia Jing, Anna Danielsson, Hana Dobsicek Trefna et al
Colloids and Surfaces B: Biointerfaces. Vol. 151, p. 112-118
Scientific journal article - peer reviewed
2016

Core−Shell Nanoplasmonic Sensing for Characterization of Biocorona Formation and Nanoparticle Surface Interactions

Rickard Frost, Carl Wadell, Anders Hellman et al
ACS Sensors. Vol. 1 (6), p. 798-806
Scientific journal article - peer reviewed
2016

TiO2 nanoparticle interactions with supported lipid membranes – an example of removal of membrane patches

Fang Zhao, Jenny Perez-Holmberg, Zareen Abbas et al
RSC Advances. Vol. 6 (94), p. 91102-91110
Scientific journal article - peer reviewed
2016

Graphene Oxide and Lipid Membranes: Size-Dependent Interactions

Rickard Frost, Sofia Svedhem, Christoph Langhammer et al
Langmuir. Vol. 32 (11), p. 2708-2717
Scientific journal article - peer reviewed
2016

Effects of Al3+ on Phosphocholine and Phosphoglycerol Containing Solid Supported Lipid Bilayers

H. K. Wayment-Steele, Yujia Jing, M. J. Swann et al
Langmuir. Vol. 32 (7), p. 1771-1781
Scientific journal article - peer reviewed
2016

Synthesis and Evaluation of Astatinated N-[2-(Maleimido)ethyl]-3-(trimethylstannyl)benzamide Immunoconjugates

Emma Aneheim, Anna Gustafsson, Per Albertsson et al
Bioconjugate chemistry. Vol. 27 (3), p. 688-97
Scientific journal article - peer reviewed
2015

Mucin-like region of herpes simplex virus type 1 attachment protein gC modulates the virus-glycosaminoglycan interaction.

Noomi Altgärde, Charlotta Eriksson, Nadia Peerboom et al
Journal of Biological Chemistry. Vol. 290 (35), p. 21473-21485
Scientific journal article - peer reviewed
2015

Non-Invasive Acoustical sensing of Drug-Induced Effects on the Contractile Machinery of Human Cardiomyocyte Clusters

Angelika Kunze, D. Steel, K. Dahlenborg et al
PLoS ONE. Vol. 10 (5), p. Art. no. e0125540
Scientific journal article - peer reviewed
2015

Heat-activated liposome targeting to streptavidin-coated surfaces

Yujia Jing, Hana Dobsicek Trefna, Mikael Persson et al
Biochimica et Biophysica Acta - Biomembranes. Vol. 1848 (6), p. 1417-1423
Scientific journal article - peer reviewed
2014

QCM-D and computational study of Al3+ effects on supported lipid bilayer structure

H. K. Wayment-Steele, L. E. Johnson, Angelika Kunze et al
Abstracts of Papers of the American Chemical Society. 247th National Spring Meeting of the American-Chemical-Society (ACS), Dallas, Mars 16-20 2014. Vol. 247
Conference paper - non peer reviewed
2014

Acoustic monitoring of changes in well-defined hyaluronan layers exposed to chondrocytes

Erik Nilebäck, Lars Enochson, Noomi Altgärde et al
Analyst. Vol. 139 (21), p. 5350-5353
Scientific journal article - peer reviewed
2014

Sensing Conformational Changes in DNA upon Ligand Binding Using QCM-D. Polyamine Condensation and Rad51 Extension of DNA Layers

Lu Sun, Karolin Frykholm, Louise Fornander et al
Journal of Physical Chemistry B. Vol. 118 (41), p. 11895-11904
Scientific journal article - peer reviewed
2014

Construction and Modeling of Concatemeric DNA Multilayers on a Planar Surface as Monitored by QCM-D and SPR

Lu Sun, Sofia Svedhem, Björn Åkerman et al
Langmuir. Vol. 30 (28), p. 8432-8441
Scientific journal article - peer reviewed
2014

Peptide-membrane interactions of arginine-tryptophan peptides probed using quartz crystal microbalance with dissipation monitoring

Hanna Rydberg, Angelika Kunze, Nils Carlsson et al
European Biophysics Journal with Biophysics Letters. Vol. 43 (6-7), p. 241-253
Scientific journal article - peer reviewed
2014

Study on multilayer structures prepared from heparin and semi-synthetic cellulose sulfates as polyanions and their influence on cellular response

N. Aggarwal, Noomi Altgärde, Sofia Svedhem et al
Colloids and Surfaces B-Biointerfaces. Vol. 116, p. 93-103
Scientific journal article - peer reviewed
2014

Phase Transition-Controlled Flip-Flop in Asymmetric Lipid Membranes

Yujia Jing, Angelika Kunze, Sofia Svedhem et al
Journal of Physical Chemistry B. Vol. 118 (9), p. 2389-2395
Scientific journal article - peer reviewed
2014

Real-time monitoring of surface-confined platelet activation on TiO2

Angelika Kunze, Camilla Hesse, Sofia Svedhem et al
Colloids and Surfaces B: Biointerfaces. Vol. 116, p. 446-451
Scientific journal article - peer reviewed
2014

Formation of supported lipid bilayers on silica: relation to lipid phase transition temperature and liposome size

Yujia Jing, Hana Dobsicek Trefna, Mikael Persson et al
Soft Matter. Vol. 10 (1), p. 187-195
Scientific journal article - peer reviewed
2013

Characterization of nanoparticle-lipid membrane interactions using QCM-D

Rickard Frost, Sofia Svedhem,
Cellular and Subcellular Nanotechnology , p. 127-137
Chapter in monograph, book
2013

Membrane interaction of tryptophan-arginine peptides with dual function

Hanna Rydberg, Angelika Kunze, Noomi Altgärde et al
European Biophysics Journal with Biophysics Letters. Vol. 42, p. S169-S169
Scientific journal article - non peer reviewed
2013

Tuning Cell Adhesion and Growth on Biomimetic Polyelectrolyte Multilayers by Variation of pH During Layer-by-Layer Assembly

N. Aggarwal, Noomi Altgärde, Sofia Svedhem et al
Macromolecular Bioscience. Vol. 13 (10), p. 1327-1338
Scientific journal article - peer reviewed
2013

Cell membrane damage and protein interaction induced by copper containing nanoparticles-Importance of the metal release process

H. L. Karlsson, P. Cronholm, Y. Hedberg et al
Toxicology. Vol. 313 (1), p. 59-69
Scientific journal article - peer reviewed
2013

Effect of Molecular Composition of Heparin and Cellulose Sulfate on Multilayer Formation and Cell Response

N. Aggarwal, Noomi Altgärde, Sofia Svedhem et al
Langmuir. Vol. 29 (45), p. 13853-13864
Scientific journal article - peer reviewed
2013

Probing the biofunctionality of biotinylated hyaluronan and chondroitin sulfate by hyaluronidase degradation and aggrecan interaction

Noomi Altgärde, Erik Nilebäck, Laura De Battice et al
Acta Biomaterialia. Vol. 9 (9), p. 8158-8166
Scientific journal article - peer reviewed
2013

Acoustical sensing of cardiomyocyte cluster beating

Nina Tymchenko, Angelika Kunze, K. Dahlenborg et al
Biochemical and Biophysical Research Communications. Vol. 435 (4), p. 520-525
Scientific journal article - peer reviewed
2013

Acoustic detection of melanosome transport in Xenopus laevis melanophores

Rickard Frost, Elisabeth Norström, Lovisa Bodin et al
Analytical Biochemistry. Vol. 435 (1), p. 10-18
Scientific journal article - peer reviewed
2013

Immobilization of chondroitin sulfate to lipid membranes and its interactions with ECM proteins

Noomi Altgärde, Jana Becher, Stephanie Möller et al
Journal of Colloid and Interface Science. Vol. 390, p. 528-266
Scientific journal article - peer reviewed
2012

QCM-D - a useful tool for cell studies?

Erik Nilebäck, Nina Tymchenko, Julie Gold et al
eCM Journal. Vol. 23 (Supplement 5), p. 52
Conference poster
2012

Well-defined lipid interfaces for protein adsorption studies

Cristina Satriano, Sofia Svedhem, Bengt Kasemo et al
Physical Chemistry Chemical Physics. Vol. 14 (48), p. 16695-16698
Scientific journal article - peer reviewed
2012

Reversible Changes in Cell Morphology due to Cytoskeletal Rearrangements Measured in Real-Time by QCM-D

Nina Tymchenko, Erik Nilebäck, Marina V. Voinova et al
Biointerphases. Vol. 7 (1-4), p. 43-
Scientific journal article - peer reviewed
2012

Graphene Oxide and Lipid Membranes: Interactions and Nanocomposite Structures

Rickard Frost, Gustav Edman Jönsson, Dinko Chakarov et al
Nano Letters. Vol. 12 (7), p. 3356-3362
Scientific journal article - peer reviewed
2012

Reversible Hybridization of DNA Anchored to a Lipid Membrane via Porphyrin

Jakob Woller, Karl Börjesson, Sofia Svedhem et al
Langmuir. Vol. 28 (4), p. 1944-1953
Scientific journal article - peer reviewed
2011

Pore spanning lipid bilayers on mesoporous silica having varying pore size

Maria Claesson, Rickard Frost, Sofia Svedhem et al
European Cells and Materials. Vol. 21 (SUPPL.1), p. 40
Conference paper - peer reviewed
2011

Imaging of blood plasma coagulation at supported lipid membranes

L. Faxalv, Jasmin Hume, Bengt Kasemo et al
Journal of Colloid and Interface Science. Vol. 364 (2), p. 582-587
Scientific journal article - peer reviewed
2011

Supported Lipid Bilayers With Controlled Curvature via Colloidal Lithography

M. Sundh, M. Manandhar, Sofia Svedhem et al
IEEE Transactions on Nanobioscience. Vol. 10 (3), p. 187-193
Scientific journal article - peer reviewed
2011

Kinetics of Ligand Binding to Membrane Receptors from Equilibrium Fluctuation Analysis of Single Binding Events

Anders Gunnarsson, L. Dexlin, Patric Wallin et al
Journal of the American Chemical Society. Vol. 133 (38), p. 14852-14855
Scientific journal article - peer reviewed
2011

Characterization and application of a surface modification designed for QCM-D studies of biotinylated biomolecules

Erik Nilebäck, Laurent Feuz, H. Uddenberg et al
Biosensors & Bioelectronics. Vol. 28 (1), p. 407-413
Scientific journal article - peer reviewed
2011

Ion-mediated changes of supported lipid bilayers and their coupling to the substrate. A case of bilayer slip?

Angelika Kunze, Fang Zhao, Anna-Kristina Marel et al
Soft Matter. Vol. 7 (18), p. 8582-8591
Scientific journal article - peer reviewed
2011

Bioreducible insulin-loaded nanoparticles and their interaction with model lipid membranes

Rickard Frost, G. Coue, J. F. J. Engbersen et al
Journal of Colloid and Interface Science. Vol. 362 (2), p. 575-583
Scientific journal article - peer reviewed
2011

The Inflammation-associated Protein TSG-6 Cross-links Hyaluronan via Hyaluronan-induced TSG-6 Oligomers

Natalia Baranova, Erik Nilebäck, M Haller et al
Journal of Biological Chemistry. Vol. 286 (29), p. 25675-25686
Scientific journal article - peer reviewed
2011

Pore Spanning Lipid Bilayers on Mesoporous Silica Having Varying Pore Size

Maria Claesson, Rickard Frost, Sofia Svedhem et al
Langmuir. Vol. 27 (14), p. 8974-8982
Scientific journal article - peer reviewed
2011

Formation of Supported Lipid Bilayers at Surfaces with Controlled Curvatures: Influence of Lipid Charge

M. Sundh, Sofia Svedhem, D. S. Sutherland et al
Journal of Physical Chemistry B. Vol. 115 (24), p. 7838-7848
Scientific journal article - peer reviewed
2011

Chemical Modifications of Au/SiO2 Template Substrates for Patterned Biofunctional Surfaces

Elisabeth Briand, V. Humblot, J. Landoulsi et al
Langmuir. Vol. 27 (2), p. 678-685
Scientific journal article - peer reviewed
2011

Electrodeless QCM-D for lipid bilayer applications

Angelika Kunze, Michael Zäch, Sofia Svedhem et al
Biosensors and Bioelectronics. Vol. 26 (5), p. 1833-1838
Scientific journal article - peer reviewed
2011

Structural Rearrangements of Polymeric Insulin-loaded Nanoparticles Interacting with Surface-Supported Model Lipid Membranes

Rickard Frost, Christian Grandfils, Bernardino Cerda et al
Journal of Biomaterials and Nanobiotechnology. Vol. 2 (2), p. 181-193
Scientific journal article - peer reviewed
2010

Nanobiomaterial - lipid membrane interactions

Rickard Frost, Bengt Kasemo, Sofia Svedhem et al
European Cells and Materials: 4th Annual Meeting of the Scandinavian Society for Biomaterials Fiskebäckskil, Sweden, May 4-6 2011. Vol. 21 (suppl. 1), p. 13-
Conference paper - peer reviewed
2010

Responsive insulin-loaded polymeric nanoparticles interacting with model lipid membranes

Rickard Frost, G. Coue, J.F.J. Engbersen et al
European Cells and Materials: 3rd International NanoBio Conference 2010, ETH Zurich, Switzerland August 24-27 2010. Vol. 20 (suppl. 3), p. 84-
Conference paper - peer reviewed
2010

Monitoring of surface interactions as a tool for nanoparticle design

Rickard Frost, C. Grandfils, Bengt Kasemo et al
Journal of controlled release : official journal of the Controlled Release Society. Vol. 148 (1), p. e36-37
Scientific journal article - peer reviewed
2010

Influence of phase separating lipids on supported lipid bilayer formation at SiO2 surfaces

M. Sundh, Sofia Svedhem, D. S. Sutherland et al
Physical Chemistry Chemical Physics. Vol. 12 (2), p. 453-460
Scientific journal article - peer reviewed
2010

Combined QCM-D and EIS study of supported lipid bilayer formation and interaction with pore-forming peptides

Elisabeth Briand, Michael Zäch, Sofia Svedhem et al
Analyst. Vol. 135 (2), p. 343-350
Scientific journal article - peer reviewed
2010

Viscoelastic Sensing of Conformational Changes in Plasminogen Induced upon Binding of Low Molecular Weight Compounds

Erik Nilebäck, F. Westberg, J. Deinum et al
Analytical Chemistry. Vol. 82 (20), p. 8374-8376
Scientific journal article - peer reviewed
2010

A miniaturized flow reaction chamber for use in combination with QCM-D sensing

Gabriel Ohlsson, Pauline Axelsson, Joshua Henry et al
Microfluidics and Nanofluidics. Vol. 9 (4-5), p. 705-716
Scientific journal article - peer reviewed
2010

An OEGylated thiol monolayer for the tethering of liposomes and the study of liposome interactions

Elisabeth Briand, V. Humblot, C. M. Pradier et al
Talanta: The International Journal of Pure and Applied Analytical Chemistry. Vol. 81 (4-5), p. 1153-1161
Scientific journal article - peer reviewed
2010

Plasma oxidized polyhydroxymethylsiloxane – a new smooth surface for supported lipid bilayer formation

Cristina Satriano, Malin Edvardsson, Gabriel Ohlsson et al
Langmuir. Vol. 26 (8), p. 5715-5725
Scientific journal article - peer reviewed
2009

In Situ Control of the Oxide Layer on Thermally Evaporated Titanium and Lysozyme Adsorption by Means of Electrochemical Quartz with Dissipation

I. Van De Keere, Sofia Svedhem, H. Hogberg et al
Acs Applied Materials & Interfaces. Vol. 1 (2), p. 301-310
Scientific journal article - peer reviewed
2009

A Novel Surface Modification Using Tissue Factor Reconstituted in Phospholipid Vesicles for the Activation of Blood Coagulation

Sofia Svedhem, A Wikström, J. Deinum et al
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION. Vol. 20 (1), p. 133-140
Scientific journal article - peer reviewed
2009

In Situ Preparation and Modification of Supported Lipid Layers by Lipid Transfer from Vesicles Studied by QCM-D and TOF-SIMS

Angelika Kunze, P. Sjövall, Bengt Kasemo et al
Journal of the American Chemical Society. Vol. 131 (7), p. 2450-2451
Scientific journal article - peer reviewed
2009

Lipid Transfer between Charged Supported Lipid Bilayers and Oppositely Charged Vesicles

Angelika Kunze, Sofia Svedhem, Bengt Kasemo et al
Langmuir. Vol. 25 (9), p. 5146-5158
Scientific journal article - peer reviewed
2009

QCM-D and reflectometry instrument - applications to supported lipid structures and their biomolecular interactions

Malin Edvardsson, Sofia Svedhem, Guoliang Wang et al
Analytical Chemistry. Vol. 81 (1), p. 349-361
Scientific journal article - peer reviewed
2008

Real-Time QCM-D Monitoring of Electrostatically Driven Lipid Transfer between Two Lipid Bilayer Membranes

Angelica Wikström, Sofia Svedhem, Marc Sivignon et al
Journal of Physical Chemistry B. Vol. 112 (44), p. 14069-14074
Scientific journal article - peer reviewed
2008

A combined reflectometry and quartz crystal microbalance with dissipation setup for surface interaction studies

G Wang, Michael Rodahl, Malin Edvardsson et al
Review of Scientific Instruments. Vol. 79 (7), p. 075107
Scientific journal article - peer reviewed
2007

Supported lipid bilayers, tethered lipid vesicles, and vesicle fusion investigated using gravimetric, plasmonic, and microscopy techniques

Fredrik Höök, G. Stengel, Andreas Dahlin et al
Biointerphases. Vol. 3 (2)
Scientific journal article - peer reviewed
2007

DHA-induced changes of supported lipid membrane morphology

Dorota Thid, Jason J. Benkoski, Sofia Svedhem et al
Langmuir. Vol. 23 (11), p. 5878-5881
Scientific journal article - peer reviewed