Current Status of COVID-19 Therapies and Drug Repositioning Applications
Review article, 2020

The rapid and global spread of a new human coronavirus (SARS-CoV-2) has produced an immediate urgency to discover promising targets for the treatment of COVID-19. Drug repositioning is an attractive approach that can facilitate the drug discovery process by repurposing existing pharmaceuticals to treat illnesses other than their primary indications. Here, we review current information concerning the global health issue of COVID-19 including promising approved drugs and ongoing clinical trials for prospective treatment options. In addition, we describe computational approaches to be used in drug repurposing and highlight examples of in silico studies of drug development efforts against SARS-CoV-2.

Health Sciences



Ozlem Altay

Royal Institute of Technology (KTH)

Elyas Mohammadi

Ferdowsi University of Mashhad

Royal Institute of Technology (KTH)

Simon Lam

King's College London

Hasan Turkez

Atatürk University

Jan Borén

Wallenberg Lab.

Jens B Nielsen

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

Mathias Uhlen

Royal Institute of Technology (KTH)

Adil Mardinoglu

King's College London

Royal Institute of Technology (KTH)


25890042 (eISSN)

Vol. 23 7 101303

Subject Categories

Pharmaceutical Sciences

Pharmacology and Toxicology

Social and Clinical Pharmacy



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