Nutritional metabolomics: Recent developments and future needs
Review article, 2023
Metabolomics has rapidly been adopted as one of the key methods in nutrition research. This review focuses on the recent developments and updates in the field, including the analytical methodologies that encompass improved instrument sensitivity, sampling techniques and data integration (multiomics). Metabolomics has advanced the discovery and validation of dietary biomarkers and their implementation in health research. Metabolomics has come to play an important role in the understanding of the role of small molecules resulting from the diet–microbiota interactions when gut microbiota research has shifted towards improving the understanding of the activity and functionality of gut microbiota rather than composition alone. Currently, metabolomics plays an emerging role in precision nutrition and the recent developments therein are discussed.
Gut microbiota
Dietary pattern
Nutrition
Metabolomics
Biomarker
Precision prevention
Endogenous metabolite
Author
Maaria Kortesniemi
University of Turku
Stefania Noerman
Chalmers, Life Sciences, Food and Nutrition Science
A. Kårlund
University of Turku
Jasmin Raita
University of Turku
Topi Meuronen
University of Turku
Ville Mikael Koistinen
University of Turku
University of Eastern Finland
Rikard Landberg
Chalmers, Life Sciences, Food and Nutrition Science
K. Hanhineva
University of Turku
University of Eastern Finland
Current Opinion in Chemical Biology
1367-5931 (ISSN) 18790402 (eISSN)
Vol. 77 102400Discovery and valdiation of novel biomarkers of gut microbiota, diet and their interactions associated with type 2 diabetes risk
Swedish Research Council (VR) (2019-01264), 2020-01-01 -- 2022-12-31.
Innovative pulse and cereal-based food fermentations for human health and sustainable diets (HealthFerm )
European Commission (EC) (101060247), 2022-09-01 -- 2026-08-31.
Dynamic longitudinal exposome trajectories in cardiovascular and metabolic non-communicable diseases’ — ‘LONGITOOLS’
European Commission (EC) (EC/H2020/874739), 2019-12-31 -- 2023-12-31.
Subject Categories
Food Science
Nutrition and Dietetics
DOI
10.1016/j.cbpa.2023.102400
PubMed
37804582