De novo production of protoberberine and benzophenanthridine alkaloids through metabolic engineering of yeast
Journal article, 2024
Author
Xiang Jiao
Chalmers, Life Sciences, Systems and Synthetic Biology
Xiaozhi Fu
Chalmers, Life Sciences, Systems and Synthetic Biology
Qishuang Li
State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences
Junling Bu
State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences
Xiuyu Liu
State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences
Otto Savolainen
Chalmers, Life Sciences, Infrastructures
Luqi Huang
State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences
Juan Guo
State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences
Jens B Nielsen
Chalmers, Life Sciences, Systems and Synthetic Biology
Yun Chen
Chalmers, Life Sciences, Systems and Synthetic Biology
Nature Communications
2041-1723 (ISSN) 20411723 (eISSN)
Vol. 15 8759-Microbial synthesis of medicinal natural products
The Swedish Foundation for International Cooperation in Research and Higher Education (STINT) (CH2019-8258), 2020-04-01 -- 2023-12-31.
Production of Benzylisoquinoline Alkaloids in Yeast
Swedish Research Council (VR) (2018-06003), 2019-01-01 -- 2021-12-31.
Subject Categories
Industrial Biotechnology
Biochemistry and Molecular Biology
Infrastructure
Chalmers Infrastructure for Mass spectrometry
DOI
10.1038/s41467-024-53045-3