A practical guide to the implementation of artificial intelligence in orthopaedic research—Part 3: How orthopaedic research benefits from the implementation of artificial intelligence
Review article, 2025

Artificial intelligence (AI) encompasses the development of systems that can perform human-like tasks, such as treatment guidance, decision-making, pattern recognition and understanding language. Within AI, machine learning and deep learning play pivotal roles in diagnosis and outcome prediction, while natural language processing aids in synthesising large datasets from the electronic medical record. In orthopaedics, AI has demonstrated success in various areas, including image evaluation, surgical planning, outcome prediction, cohort identification and administrative tasks. The purpose of this manuscript was to provide an overview of the benefits of AI implementation within the field of orthopaedics. An additional goal was to address the challenges associated with producing high quality AI-based research in a rapidly developing field. Level of Evidence: Level IV.

orthopaedics

research methods

machine learning

artificial intelligence

sports medicine

Author

James Pruneski

Tripler Army Medical Center

Ayoosh Pareek

Hospital for Special Surgery

Bálint Zsidai

Sahlgrenska University Hospital

University of Gothenburg

Skåne University Hospital

Jacob F. Oeding

University of Gothenburg

Mayo Clinic

Jonathan D. Hughes

University of Pittsburgh

Felix C. Oettl

University of Zürich

Philipp W. Winkler

Johannes Kepler University of Linz (JKU)

Thomas Tischer

Malteser Waldkrankenhaus Erlangen

University of Rostock

Elmar Herbst

University Hospital Muenster

Alberto Grassi

IRCCS Istituto Ortopedico Rizzoli, Bologna

Michael T. Hirschmann

University of Basel

Canton Hospital Basel-Land

Christophe Ley

University of Luxembourg

Yinan Yu

Chalmers, Computer Science and Engineering (Chalmers), Functional Programming

University of Gothenburg

Kristian Samuelsson

Sahlgrenska University Hospital

University of Gothenburg

Journal of Experimental Orthopaedics

2197-1153 (eISSN)

Vol. 12 4 e70481

Subject Categories (SSIF 2025)

Orthopaedics

DOI

10.1002/jeo2.70481

PubMed

41180563

More information

Latest update

5/20/2026