CRISPRi teknik för finjustering av jästens stress reglering
Forskningsprojekt, 2018
– 2019
In this project, we will use the cutting-edge CRISPRi technology, for developing robust industrial yeast strains for the production of bioethanol and other biofuels- and chemicals. Using the CRISPRi technology we will elucidate the stress responses of yeast. This knowledge can be used for engineering novel production strains. Robust, stress-tolerant yeast for the cost-effective production of renewable energy carriers are needed for reaching Sweden’s targets for a fossil-free fleet by 2030. Today, the main challenge for making biofuels and chemicals from lignocellulosic biomass, made from residues from agriculture and forestry, is the presence of inhibitors that are toxic for the cells and cause severe stress that lower the productivity.
Deltagare
Vaskar Mukherjee (kontakt)
Chalmers, Life sciences, Industriell bioteknik
Yvonne Nygård
Chalmers, Life sciences, Industriell bioteknik
Samarbetspartners
Göteborgs universitet
Gothenburg, Sweden
Stanford University
Stanford, USA
Finansiering
Chalmers
Finansierar Chalmers deltagande under 2018–2019
Kungliga vetenskapsakademien
Finansierar Chalmers deltagande under 2018–2019
Stiftelsen Wilhelm och Martina Lundgrens Vetenskapsfond
Finansierar Chalmers deltagande under 2018–2019
Relaterade styrkeområden och infrastruktur
Energi
Styrkeområden