CRISPRi teknik för finjustering av jästens stress reglering
Forskningsprojekt , 2018 – 2019

In this project, we will use the cutting-edge CRISPRi technology, for developing robust industrial yeast strains for the production of bioethanol and other biofuels- and chemicals. Using the CRISPRi technology we will elucidate the stress responses of yeast. This knowledge can be used for engineering novel production strains. Robust, stress-tolerant yeast for the cost-effective production of renewable energy carriers are needed for reaching Sweden’s targets for a fossil-free fleet by 2030. Today, the main challenge for making biofuels and chemicals from lignocellulosic biomass, made from residues from agriculture and forestry, is the presence of inhibitors that are toxic for the cells and cause severe stress that lower the productivity.

Deltagare

Vaskar Mukherjee (kontakt)

Doktor vid Chalmers, Biologi och bioteknik, Industriell bioteknik

Yvonne Nygård

Forskarassistent vid Chalmers, Biologi och bioteknik, Industriell bioteknik

Samarbetspartners

Göteborgs universitet

Gothenburg, Sweden

Stanford University

Stanford, USA

Finansiering

Stiftelsen Wilhelm och Martina Lundgrens Vetenskapsfond

Finansierar Chalmers deltagande under 2018–2019

Kungliga vetenskapsakademien

Finansierar Chalmers deltagande under 2018–2019

Chalmers

Finansierar Chalmers deltagande under 2018–2019

Relaterade styrkeområden och infrastruktur

Energi

Styrkeområden

Publikationer

Mer information

Senast uppdaterat

2018-10-24