Oscillatory kinetics of gene expression: Protein conversion and slow mRNA transport
Artikel i vetenskaplig tidskrift, 2009

The negative feedback between mRNA and regulatory-protein production may result in oscillations in the kinetics of gene expression if the mRNA-protein interplay includes protein conversion. Using a mean-field kinetic model, we show that such oscillations can be amplified due to limitations of the mRNA transport between the nucleus and cytoplasm. This effect may be dramatic for the mRNA population in the nucleus.

Författare

Vladimir Zhdanov

Chalmers, Teknisk fysik, Kemisk fysik

Journal of Experimental and Theoretical Physics

1063-7761 (ISSN) 1090-6509 (eISSN)

Vol. 108 1050-1053

Ämneskategorier

Atom- och molekylfysik och optik

DOI

10.1134/S106377610906017X