Estimation of the PCR efficiency based on a size-dependent modelling of the amplification process
Artikel i vetenskaplig tidskrift, 2005

We propose a stochastic modelling of the PCR amplification process by a size-dependent branching process starting as a supercritical Bienaymé-Galton-Watson transient phase and then having a saturation near-critical size-dependent phase. This model based on the concept of saturation allows one to estimate the probability of replication of a DNA molecule at each cycle of a single PCR trajectory with a very good accuracy.


Nadia Lalam

University of North Texas

C. Jacob

INRA Institut National de La Recherche Agronomique

Peter Jagers

Göteborgs universitet

Chalmers, Matematiska vetenskaper, matematisk statistik

Comptes Rendus Mathematique

1631-073X (ISSN)

Vol. 341 631-634


Sannolikhetsteori och statistik