Estimation of the PCR efficiency based on a size-dependent modelling of the amplification process
Artikel i vetenskaplig tidskrift, 2005

We propose a stochastic modelling of the PCR amplification process by a size-dependent branching process starting as a supercritical Bienaymé-Galton-Watson transient phase and then having a saturation near-critical size-dependent phase. This model based on the concept of saturation allows one to estimate the probability of replication of a DNA molecule at each cycle of a single PCR trajectory with a very good accuracy.

Författare

Nadia Lalam

University of North Texas

C. Jacob

Institut national de la recherche agronomique (INRA)

Peter Jagers

Göteborgs universitet

Chalmers, Matematiska vetenskaper, Matematisk statistik

Publicerad i

Comptes Rendus Mathematique

1631-073X (ISSN)

Vol. 341 Nummer/häfte 10 s. 631-634

Kategorisering

Ämneskategorier (SSIF 2011)

Sannolikhetsteori och statistik

Identifikatorer

DOI

10.1016/j.crma.2005.09.029

Mer information

Senast uppdaterat

2020-12-01