Saccharomyces cerevisiae Spore Germination
Kapitel i bok, 2010

Saccharomyces cerevisiae spore germination is the process in which dormant spores resume growth. Upon exposure to glucose and other essential nutrients, the spore gradually loses its spore characteristics and starts acquiring properties of a vegetative cell. Translation and transcription are initiated early in the germination process. Global gene expression analysis has revealed that germination can be divided into two stages prior to the first cell cycle. During the first stage, the transcriptional programme resembles the general response of yeast cells to glucose. During the second stage, the spores sense and respond also to other nutrients than glucose. In addition, genes involved in conjugation are upregulated in germinating spores and mating is initiated before the first mitotic cell cycle. Here, we review the current understanding of the cellular rearrangements and the genes and proteins involved in germination.


Cecilia Geijer

Göteborgs universitet

Daphna Joseph-Strauss

Gloria Simchen

Naama Barkai

Stefan Hohmann

Göteborgs universitet

Dormancy and Resistance in Harsh Environments, Topics in Current Genetics, Volume 21/2010; editors: Esther Lubzens, Joan Cerda and Melody Clark



Biokemi och molekylärbiologi



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