Robust Gain-Scheduled Controller Design for T1DM Individualised Model
Paper i proceeding, 2015

Novel original robust gain-scheduled controller design for individualized type 1 diabetes mellitus (T1DM) subject model is presented in this paper. For controller design an LPV model is created from insulin-glucose subsystem based on Bergman’s minimal model with subcutaneous insulin absorption and absorption of digested carbohydrates. Identification was performed on pharmacokinetics and pharmacodynamics characteristics of administered insulin and data collected from continuous glucose monitoring (CGM) system. The controller design approach guarantees the closed-loop stability and cost for all scheduled parameter changes. Simulation results show the benefits of the proposed approach.

Quadratic stability

Output feedback

Robust controller

LPV system

Type 1 diabetes mellitus model



Adrian Ilka

Chalmers, Signaler och system, Signalbehandling och medicinsk teknik

Tomas Ludwig

Unknown organization

Ivan Ottinger

Unknown organization

Marián Tárník

Unknown organization

Eva Miklovicová

Unknown organization

Vojtech Veselý

Slovak University of Technology Bratislava

Ján Murgas

Unknown organization


2405-8963 (ISSN)

Vol. 48 14 82-87