MgO implanted in rat tibia bone marrow is osteoinductive through the formation of a matrix, containing hydroxyapatite
Paper i proceeding, 2017

Healing of rat tibia after intramedullary implantation of MgO was analysed by Environmental Scanning Electron Microscopy (ESEM) and Energy-Dispersive X-ray spectroscopy (EDX). The results indicated the formation of hydroxyl-apatite (HA) in the entire intramedullary space after 1 week of healing. Then, corroded Mg, MgO and MgCO3 were incubated with DMEM in vitro for 24 h and the surface of the material was analysed by EDX and Time-of-Flight Secondary Ion Mass (ToF-SIMS). The chemical analysis of the Mg corrosion products indicate that HA is formed at the material surface and that MgCO3 was an efficient catalyzer of HA formation. © 2017 Trans Tech Publications, Switzerland.

Hydroxyl-apatite

Bone cement

Magnesium

Bone healing

Författare

Håkan Nygren

Göteborgs universitet

Per Malmberg

Loughborough University

Yang Liu

Chalmers, Kemi och kemiteknik, Kemi och biokemi, Analytisk kemi

Materials Science Forum

0255-5476 (ISSN)

Vol. 879 1404-1407

Ämneskategorier

Analytisk kemi

DOI

10.4028/www.scientific.net/MSF.879.1404

ISBN

9783035711295