Selection of complementary foods based on optimal nutritional values
Artikel i vetenskaplig tidskrift, 2017

Human milk is beneficial for growth and development of infants. Several factors result in mothers ceasing breastfeeding which leads to introduction of breast-milk substitutes (BMS). In some communities traditional foods are given as BMS, in others they are given as complementary foods during weaning. Improper food selection at this stage is associated with a high prevalence of malnutrition in children under 5 years. Here we listed the traditional foods from four continents and compared them with human milk based on their dietary contents. Vitamins such as thiamine (similar to[2-10] folds), riboflavin (similar to[4-10] folds) and ascorbic acid (< 2 folds) contents of Asian and African foods were markedly lower. In order to extend the search for foods that includes similar dietary constituents as human milk, we designed a strategy of screening 8654 foods. 12 foods were identified and these foods were evaluated for their ability to meet the daily nutritional requirement of breastfed and nonbreastfed infants during their first year of life. Genome-scale models of infant's hepatocytes, adipocytes and myocytes were then used to simulate in vitro growth of tissues when subjected to these foods. Key findings were that pork ham cured, fish pudding, and egg lean white induced better tissue growth, and quark with fruit, cheese quarg 45% and cheese cream 60% had similar lactose content as human milk.




Metabolic Network




Nutrient Density


Feeding Practices


Partho Sen

Chalmers, Biologi och bioteknik, Systembiologi

Adil Mardinoglu

Chalmers, Biologi och bioteknik, Systembiologi

Jens B Nielsen

Chalmers, Biologi och bioteknik, Systembiologi

Scientific Reports

2045-2322 (ISSN) 20452322 (eISSN)

Vol. 7 1 Article no 5413 - 5413


Biologiska vetenskaper



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