Interlaboratory coverage test on plant food bioactive compounds and their metabolites by mass spectrometry-based untargeted metabolomics
Artikel i vetenskaplig tidskrift, 2018

Bioactive compounds present in plant-based foods, and their metabolites derived from gut microbiota and endogenous metabolism, represent thousands of chemical structures of potential interest for human nutrition and health. State-of-the-art analytical methodologies, including untargeted metabolomics based on high-resolution mass spectrometry, are required for the profiling of these compounds in complex matrices, including plant food materials and biofluids. The aim of this project was to compare the analytical coverage of untargeted metabolomics methods independently developed and employed in various European platforms. In total, 56 chemical standards representing the most common classes of bioactive compounds spread over a wide chemical space were selected and analyzed by the participating platforms (n = 13) using their preferred untargeted method. The results were used to define analytical criteria for a successful analysis of plant food bioactives. Furthermore, they will serve as a basis for an optimized consensus method.

Mass spectrometry

Method development

Phytochemicals

Författare

Ville Mikael Koistinen

Itä-Suomen Yliopisto

Andreia Bento da Silva

Universidade NOVA de Lisboa

László Abrankó

Szent Istvan Egyetem

Dorrain Low

Universite d' Auvergne Clermont-FD 1

Rocio Garcia Villalba

CEBAS- CSIC, Centro de Edafología y Biología Aplicada del Segura

Francisco Tomás Barberán

CEBAS- CSIC, Centro de Edafología y Biología Aplicada del Segura

Rikard Landberg

Chalmers, Biologi och bioteknik, Livsmedelsvetenskap

Forskning Andra publikationer

Otto Savolainen

Chalmers, Biologi och bioteknik, Livsmedelsvetenskap

Forskning Andra publikationer

Inmaculada Alvarez-Acero

CSIC - Instituto de Ciencia y Tecnologia de Alimentos y Nutricion (ICTAN)

Sonia de Pascual-Teresa

CSIC - Instituto de Ciencia y Tecnologia de Alimentos y Nutricion (ICTAN)

Christof Van Poucke

Instituut voor Landbouw- en Visserijonderzoek

Conceição Almeida

Universidade NOVA de Lisboa

Lucie Petrásková

Czech Academy of Sciences

Kateřina Valentová

Czech Academy of Sciences

Stephanie Durand

Universite d' Auvergne Clermont-FD 1

Wiesław Wiczkowski

Polish Academy of Sciences

Dorota Szawara-Nowak

Polish Academy of Sciences

Raúl González-Domínguez

Instituto de Salud Carlos III

Universitat de Barcelona

Teknologian Tutkimuskeskus (VTT)

Rafael Llorach

Instituto de Salud Carlos III

Teknologian Tutkimuskeskus (VTT)

Universitat de Barcelona

Cristina Andres-Lacueva

Instituto de Salud Carlos III

Universitat de Barcelona

Teknologian Tutkimuskeskus (VTT)

Anna-Marja Aura

Instituto de Biologia Experimental e Tecnologica

Tuulikki Seppänen-Laakso

Instituto de Biologia Experimental e Tecnologica

K. Hanhineva

Itä-Suomen Yliopisto

Claudine Manach

Universite d' Auvergne Clermont-FD 1

Maria Rosário Bronze

Universidade NOVA de Lisboa

Universidade de Lisboa

Metabolites

2218-1989 (ISSN)

Vol. 8 3 46

Ämneskategorier

Analytisk kemi

Livsmedelsvetenskap

Miljövetenskap

DOI

10.3390/metabo8030046

Publikationsdata kopplat till DOI

Mer information

Senast uppdaterat

2019-12-03

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