Coffee and tea consumption and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition
Artikel i vetenskaplig tidskrift, 2019

The epidemiological evidence regarding the association of coffee and tea consumption with prostate cancer risk is inconclusive, and few cohort studies have assessed these associations by disease stage and grade. We examined the associations of coffee (total, caffeinated and decaffeinated) and tea intake with prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition. Among 142,196 men, 7,036 incident prostate cancer cases were diagnosed over 14 years of follow-up. Data on coffee and tea consumption were collected through validated country-specific food questionnaires at baseline. We used Cox proportional hazards regression models to compute hazard ratios (HRs) and 95% confidence intervals (CI). Models were stratified by center and age, and adjusted for anthropometric, lifestyle and dietary factors. Median coffee and tea intake were 375 and 106 mL/day, respectively, but large variations existed by country. Comparing the highest (median of 855 mL/day) versus lowest (median of 103 mL/day) consumers of coffee and tea (450 vs. 12 mL/day) the HRs were 1.02 (95% CI, 0.94–1.09) and 0.98 (95% CI, 0.90–1.07) for risk of total prostate cancer and 0.97 (95% CI, 0.79–1.21) and 0.89 (95% CI, 0.70–1.13) for risk of fatal disease, respectively. No evidence of association was seen for consumption of total, caffeinated or decaffeinated coffee or tea and risk of total prostate cancer or cancer by stage, grade or fatality in this large cohort. Further investigations are needed to clarify whether an association exists by different preparations or by concentrations and constituents of these beverages.

caffeinated

EPIC

coffee

prostate cancer

tea

decaffeinated

Författare

Abhijit Sen

Norges teknisk-naturvitenskapelige universitet

University of Ioannina

Nikos Papadimitriou

University of Ioannina

Pagona Lagiou

University of Athens

Harvard School of Public Health

Academy of Athens

Aurora Perez-Cornago

University of Oxford

Ruth C. Travis

University of Oxford

Timothy J. Key

University of Oxford

Neil Murphy

International Agency for Research on Cancer

Marc Gunter

International Agency for Research on Cancer

Heinz Freisling

International Agency for Research on Cancer

Ioanna Tzoulaki

University of Ioannina

Imperial College London

David C. Muller

Imperial College London

Amanda J. Cross

Imperial College London

David S. Lopez

University of Texas School of Public Health

University of Texas Medical School

Manuela Bergmann

German Institute of Human Nutrition

Heiner Boeing

German Institute of Human Nutrition

Christina Bamia

Hellenic Health Foundation, Athens

University of Athens

Anastasia Kotanidou

University of Athens Medical School

Hellenic Health Foundation, Athens

Anna Karakatsani

Hellenic Health Foundation, Athens

University of Athens

Anne Tjønneland

Danish Cancer Research Society Center

C. Kyro

Danish Cancer Research Society Center

Malene Outzen

Danish Cancer Research Society Center

María Luisa Redondo

Public Health Directorate

Valerie Cayssials

Institut d'Investigació Biomedica de Bellvitge

Maria Dolores Chirlaque

Universidad de Murcia

CIBER in Epidemiology and Public Health (CIBERESP)

Health Council of Murcia

Aurelio Barricarte

CIBER in Epidemiology and Public Health (CIBERESP)

Navarra Public Health Institute

Navarra Institute for Health Research (IdiSNA)

Maria Jose Sánchez

Escuela Andaluza Salud Publica

CIBER in Epidemiology and Public Health (CIBERESP)

Nerea Larrañaga

Public Health Division of Gipuzkoa

CIBER in Epidemiology and Public Health (CIBERESP)

Rosario Tumino

Azienda Ospedaliera Civile M.P. Arezzo

Sara Grioni

Fondazione IRCCS Istituto Nazionale dei Tumori, Milan

Domenico Palli

Centro Per Lo Studio E La Prevenzione Oncologica

Saverio Caini

Centro Per Lo Studio E La Prevenzione Oncologica

Carlotta Sacerdote

Azienda Ospedaliera - Universitaria Città della Salute e della Scienza di Torino

Bas Bueno-de-Mesquita

National Institute of Public Health and the Environment

Imperial College London

University of Malaya

University Medical Center Utrecht

Tilman Kühn

Deutsches Krebsforschungszentrum (DKFZ)

Rudolf Kaaks

Deutsches Krebsforschungszentrum (DKFZ)

Lena Nilsson

Umeå universitet

Rikard Landberg

Chalmers, Biologi och bioteknik, Livsmedelsvetenskap

Umeå universitet

Peter Wallström

Lunds universitet

Isabel Drake

Lunds universitet

Bodil Hammer Bech

Aarhus Universitet

K. Overvad

Aarhus Universitet

Dagfinn Aune

Bjørknes University College

Imperial College London

Kay Tee Khaw

University of Cambridge

Elio Riboli

Imperial College London

Dimitrios Trichopoulos

Hellenic Health Foundation, Athens

Harvard School of Public Health

Antonia Trichopoulou

University of Athens

Hellenic Health Foundation, Athens

Konstantinos K. Tsilidis

University of Ioannina

Imperial College London

International Journal of Cancer

0020-7136 (ISSN) 1097-0215 (eISSN)

Vol. 144 2 240-250

Ämneskategorier

Urologi och njurmedicin

Cancer och onkologi

Näringslära

DOI

10.1002/ijc.31634

Mer information

Senast uppdaterat

2018-12-18