Harnessing xylose pathways for biofuels production
Reviewartikel, 2019

Energy security, environmental pollution, and economic development drive the development of alternatives to fossil fuels as an urgent global priority. Lignocellulosic biomass has the potential to contribute to meeting the demand for biofuel production via hydrolysis and fermentation of released sugars, such as glucose, xylose, and arabinose. Construction of robust cell factories requires introducing and rewiring of their metabolism to efficiently use all these sugars. Here, we review recent advances in re-constructing pathways for metabolism of pentoses, with special focus on xylose metabolism in the most widely used cell factories Saccharomyces cerevisiae and Escherichia coli. We also highlight engineering advanced biofuels-synthesis pathways and describes progress toward overcoming the challenges facing adoption of large-scale biofuel production.

Fossil fuels

Escherichia coli

Energy security

Författare

Xiaowei Li

Yun Chen

Chalmers, Biologi och bioteknik, Systembiologi

Jens Christian Froslev Nielsen

Danmarks Tekniske Universitet (DTU)

Chalmers, Biologi och bioteknik, Systembiologi

Current Opinion in Biotechnology

0958-1669 (ISSN)

Vol. 57 56-65

Ämneskategorier

Förnyelsebar bioenergi

Bioenergi

Energisystem

DOI

10.1016/j.copbio.2019.01.006

Mer information

Senast uppdaterat

2019-03-12