Jens Christian Froslev Nielsen

Visar 22 publikationer

2020

Pathway engineering in yeast for synthesizing the complex polyketide bikaverin

Meng Zhao, Yu Zhao, Mingdong Yao et al
Nature Communications. Vol. 11 (1)
Artikel i vetenskaplig tidskrift
2019

Comparative Transcriptome Analysis Shows Conserved Metabolic Regulation during Production of Secondary Metabolites in Filamentous Fungi

Jens Christian Froslev Nielsen, Sylvain Prigent, Sietske Grijseels et al
mSystems. Vol. 4 (2)
Artikel i vetenskaplig tidskrift
2019

Heterologous phosphoketolase expression redirects flux towards acetate, perturbs sugar phosphate pools and increases respiratory demand in Saccharomyces cerevisiae

Alexandra Linda Bergman, John Hellgren, Thomas Moritz et al
Microbial Cell Factories. Vol. 18 (1)
Artikel i vetenskaplig tidskrift
2019

A gRNA-tRNA array for CRISPR-Cas9 based rapid multiplexed genome editing in Saccharomyces cerevisiae

Yueping Zhang, Juan Wang, Zibai Wang et al
Nature Communications. Vol. 10 (1)
Artikel i vetenskaplig tidskrift
2019

Harnessing xylose pathways for biofuels production

Xiaowei Li, Yun Chen, Jens Christian Froslev Nielsen
Current Opinion in Biotechnology. Vol. 57, p. 56-65
Reviewartikel
2019

Strategies and challenges for metabolic rewiring

Tao Yu, Yasaman Dabirian, Quanli Liu et al
Current Opinion in Systems Biology. Vol. 15, p. 30-38
Reviewartikel
2019

Synthetic Biology of Yeast

Zihe Liu, Yueping Zhang, Jens Christian Froslev Nielsen
Biochemistry. Vol. 58 (11), p. 1511-1520
Reviewartikel
2019

Pyruvate kinase L/R is a regulator of lipid metabolism and mitochondrial function

Zhengtao Liu, C. Zhang, Sunjae Lee et al
Metabolic Engineering. Vol. 52, p. 263-272
Artikel i vetenskaplig tidskrift
2019

Simplified Intestinal Microbiota to Study Microbe-Diet-Host Interactions in a Mouse Model

P. Kovatcheva-Datchary, Saeed Shoaie, Sunjae Lee et al
Cell Reports. Vol. 26 (13), p. 3772-3783.e6
Artikel i vetenskaplig tidskrift
2019

Lipid engineering combined with systematic metabolic engineering of Saccharomyces cerevisiae for high-yield production of lycopene

Tian Ma, Bin Shi, Ziling Ye et al
Metabolic Engineering. Vol. 52, p. 134-142
Artikel i vetenskaplig tidskrift
2019

Construction of mini-chemostats for high-throughput strain characterization

David Bergenholm, Guodong Liu, David Hansson et al
Biotechnology and Bioengineering. Vol. 116 (5), p. 1029-1038
Artikel i vetenskaplig tidskrift
2018

Modulation of saturation and chain length of fatty acids in Saccharomyces cerevisiae for production of cocoa butter-like lipids

David Bergenholm, Michael Gossing, Yongjun Wei et al
Biotechnology and Bioengineering. Vol. 115 (4), p. 932-942
Artikel i vetenskaplig tidskrift
2018

Reconstruction of 24 Penicillium genome-scale metabolic models shows diversity based on their secondary metabolism

Sylvain Prigent, Jens Christian Froslev Nielsen, J. C. Frisvad et al
Biotechnology and Bioengineering. Vol. 115 (10), p. 2604-2612
Artikel i vetenskaplig tidskrift
2018

Systems Biology of the Secondary Metabolism in Filamentous Fungi

Jens Christian Froslev Nielsen
Doktorsavhandling
2018

Modular Pathway Rewiring of Yeast for Amino Acid Production

Quanli Liu, Tao Yu, Kate Campbell et al
Methods in Enzymology. Vol. 608, p. 417-439
Kapitel i bok
2018

Identification of the decumbenone biosynthetic gene cluster in penicillium decumbens and the importance for production of calbistrin

S. Grijseels, Carsten Pohl, Jens Christian Froslev Nielsen et al
Fungal Biology and Biotechnology. Vol. 5 (1), p. 1-17
Artikel i vetenskaplig tidskrift
2018

Recon3D enables a three-dimensional view of gene variation in human metabolism

Elizabeth Brunk, S. Sahoo, Daniel C. Zielinski et al
Nature Biotechnology. Vol. 36 (3), p. 272-281
Artikel i vetenskaplig tidskrift
2017

Global analysis of biosynthetic gene clusters reveals vast potential of secondary metabolite production in Penicillium species

Jens Christian Froslev Nielsen, S. Grijseels, Sylvain Prigent et al
Nature Microbiology. Vol. 2 (6)
Artikel i vetenskaplig tidskrift
2017

Development of fungal cell factories for the production of secondary metabolites: Linking genomics and metabolism

Jens Christian Froslev Nielsen, Jens B Nielsen
Synthetic and Systems Biotechnology. Vol. 2 (1), p. 5-12
Reviewartikel
2017

Physiological characterization of secondary metabolite producing Penicillium cell factories

S. Grijseels, Jens Christian Froslev Nielsen, Jens B Nielsen et al
Fungal Biology and Biotechnology. Vol. 4, p. 8-
Artikel i vetenskaplig tidskrift
2017

Industrial antifoam agents impair ethanol fermentation and induce stress responses in yeast cells

Jens Christian Froslev Nielsen, F. S. D. Lino, T. G. Rasmussen et al
Applied Microbiology and Biotechnology. Vol. 101 (22), p. 8237-8248
Artikel i vetenskaplig tidskrift
2016

Penicillium arizonense, a new, genome sequenced fungal species, reveals a high chemical diversity in secreted metabolites

S. Grijseels, Jens Christian Froslev Nielsen, Jens B Nielsen et al
Scientific Reports. Vol. 6
Artikel i vetenskaplig tidskrift

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