Yun Chen

Senior forskare vid Systembiologi

Yun Chen tillhör gruppen systembiologi. Se den engelska sidan för mer information.

Källa: chalmers.se
Image of Yun Chen

Visar 67 publikationer

2024

De novo production of protoberberine and benzophenanthridine alkaloids through metabolic engineering of yeast

Xiang Jiao, Xiaozhi Fu, Qishuang Li et al
Nature Communications. Vol. 15, p. 8759-
Artikel i vetenskaplig tidskrift
2024

Increased CO<inf>2</inf> fixation enables high carbon-yield production of 3-hydroxypropionic acid in yeast

Ning Qin, Lingyun Li, Xiaozhen Wan et al
Nature Communications. Vol. 15 (1)
Artikel i vetenskaplig tidskrift
2024

Relieving metabolic burden to improve robustness and bioproduction by industrial microorganisms

Jiwei Mao, Hongyu Zhang, Yu Chen et al
Biotechnology Advances. Vol. 74
Reviewartikel
2024

Identification of the cytochrome P450s responsible for the biosynthesis of two types of aporphine alkaloids and their de novo biosynthesis in yeast

Qishuang Li, Xiang Jiao, Xinyi Li et al
Journal of Integrative Plant Biology. Vol. 66 (8), p. 1703-1717
Artikel i vetenskaplig tidskrift
2024

Phylogenetic analysis and functional characterization of norcoclaurine synthase involved in benzylisoquinoline alkaloids biosynthesis in Stephania tetrandra

Xinyi Li, Qishuang Li, Xiang Jiao et al
Journal of Cellular Physiology. Vol. 239 (10)
Artikel i vetenskaplig tidskrift
2024

Characterization of CYP82 genes involved in the biosynthesis of structurally diverse benzylisoquinoline alkaloids in Corydalis yanhusuo

Xiuyu Liu, Ying Ma, Junling Bu et al
Plant Molecular Biology. Vol. 114 (2)
Artikel i vetenskaplig tidskrift
2023

Cinnamic acid and p-coumaric acid are metabolized to 4-hydroxybenzoic acid by Yarrowia lipolytica

Oliver Konzock, Marta Tous Mohedano, Irene Cibin et al
AMB Express. Vol. 13 (1)
Artikel i vetenskaplig tidskrift
2023

Structure-function analysis of CYP719As involved in methylenedioxy bridge-formation in the biosynthesis of benzylisoquinoline alkaloids and its de novo production

Xiuyu Liu, Xiang Jiao, Yatian Cheng et al
Microbial Cell Factories. Vol. 22 (1)
Artikel i vetenskaplig tidskrift
2023

Fine-tuning of p-coumaric acid synthesis to increase (2S)-naringenin production in yeast

Jiwei Mao, Marta Tous Mohedano, Jing Fu et al
Metabolic Engineering. Vol. 79, p. 192-202
Artikel i vetenskaplig tidskrift
2023

Flux regulation through glycolysis and respiration is balanced by inositol pyrophosphates in yeast

Ning Qin, Lingyun Li, Xu Ji et al
Cell. Vol. 186 (4), p. 748-763.e15
Artikel i vetenskaplig tidskrift
2023

Restricting Promiscuity of Plant Flavonoid 3'-Hydroxylase and 4'-O-Methyltransferase Improves the Biosynthesis of (2S)-Hesperetin in E. coli

Juan Liu, Zhiqiang Xiao, Siqi Zhang et al
Journal of Agricultural and Food Chemistry. Vol. 71 (25), p. 9826-9835
Artikel i vetenskaplig tidskrift
2023

Reprogramming methanol utilization pathways to convert Saccharomyces cerevisiae to a synthetic methylotroph

Chunjun Zhan, Xiaowei Li, Guangxu Lan et al
Nature Catalysis. Vol. 6 (5), p. 435-450
Artikel i vetenskaplig tidskrift
2023

Optimizing yeast for high-level production of kaempferol and quercetin

Musa Tartik, Juan Liu, Marta Tous Mohedano et al
Microbial Cell Factories. Vol. 22 (1)
Artikel i vetenskaplig tidskrift
2023

Optimization of Pinocembrin Biosynthesis in Saccharomyces cerevisiae

Marta Tous Mohedano, Jiwei Mao, Yun Chen
ACS Synthetic Biology. Vol. 12 (1), p. 144-152
Artikel i vetenskaplig tidskrift
2023

Metabolic engineering: Tools and applications

Yun Chen, Jiazhang Lian, J. Hou
Engineering Microbiology. Vol. 3 (4)
Övrig text i vetenskaplig tidskrift
2023

A highly efficient transcriptome-based biosynthesis of non-ethanol chemicals in Crabtree negative Saccharomyces cerevisiae

Zhen Yao, Yufeng Guo, Huan Wang et al
Biotechnology for Biofuels and Bioproducts. Vol. 16 (1)
Artikel i vetenskaplig tidskrift
2022

Catalytic promiscuity of O-methyltransferases from Corydalis yanhusuo leading to the structural diversity of benzylisoquinoline alkaloids

Junling Bu, Xiuhua Zhang, Qishuang Li et al
Horticulture Research. Vol. 9
Artikel i vetenskaplig tidskrift
2022

Metabolic reconfiguration enables synthetic reductive metabolism in yeast

Tao Yu, Quanli Liu, Xiang Wang et al
Nature Metabolism. Vol. 4 (11), p. 1551-1559
Artikel i vetenskaplig tidskrift
2022

Editorial: Genomic strategies for efficient microbial cell factories

Eugene Fletcher, Yun Chen, Luis Caspeta-Guadarrama et al
Frontiers in Bioengineering and Biotechnology. Vol. 10
Övrig text i vetenskaplig tidskrift
2022

Strategies to increase tolerance and robustness of industrial microorganisms

Marta Tous Mohedano, Oliver Konzock, Yun Chen
Synthetic and Systems Biotechnology. Vol. 7 (1), p. 533-540
Artikel i vetenskaplig tidskrift
2021

Metabolic network remodelling enhances yeast’s fitness on xylose using aerobic glycolysis

Xiaowei Li, Yanyan Wang, Gang Li et al
Nature Catalysis. Vol. 4 (9), p. 783-796
Artikel i vetenskaplig tidskrift
2021

Functional characterization of (S)–N-methylcoclaurine 3′-hydroxylase (NMCH) involved in the biosynthesis of benzylisoquinoline alkaloids in Corydalis yanhusuo

Xiuyu Liu, Junling Bu, Ying Ma et al
Plant Physiology and Biochemistry. Vol. 168, p. 507-515
Artikel i vetenskaplig tidskrift
2021

Metabolic Engineering of Yeast

Rui Pereira, Olena Ishchuk, Xiaowei Li et al
Metabolic Engineering: Concepts and Applications: Volume 13a and 13b. Vol. 13, p. 689-733
Kapitel i bok
2021

Yeast optimizes metal utilization based on metabolic network and enzyme kinetics

Yu Chen, Feiran Li, Jiwei Mao et al
Proceedings of the National Academy of Sciences of the United States of America. Vol. 118 (12)
Artikel i vetenskaplig tidskrift
2021

De novo biosynthesis of bioactive isoflavonoids by engineered yeast cell factories

Quanli Liu, Yi Liu, Gang Li et al
Nature Communications. Vol. 12 (1)
Artikel i vetenskaplig tidskrift
2021

Strategies and challenges with the microbial conversion of methanol to high-value chemicals

Chunjun Zhan, Xiaowei Li, Yankun Yang et al
Biotechnology and Bioengineering. Vol. 118 (10), p. 3655-3668
Reviewartikel
2020

Multidimensional engineering of Saccharomyces cerevisiae for efficient synthesis of medium-chain fatty acids

Zhu Zhiwei, Yating Hu, Paulo Teixeira et al
Nature Catalysis. Vol. 3 (1), p. 64-74
Artikel i vetenskaplig tidskrift
2020

Elucidating aromatic acid tolerance at low pH in Saccharomyces cerevisiae using adaptive laboratory evolution

Rui Pereira, Elsayed Mohamed, Mohammad Radi et al
Proceedings of the National Academy of Sciences of the United States of America. Vol. 117 (45), p. 27954-27961
Artikel i vetenskaplig tidskrift
2020

Current state of aromatics production using yeast: achievements and challenges

Quanli Liu, Yi Liu, Yun Chen et al
Current Opinion in Biotechnology. Vol. 65, p. 65-74
Reviewartikel
2020

Rewiring Central Carbon Metabolism Ensures Increased Provision of Acetyl-CoA and NADPH Required for 3-OH-Propionic Acid Production

Ning Qin, Lingyun Li, Xu Ji et al
ACS Synthetic Biology. Vol. 9 (12), p. 3236-3244
Artikel i vetenskaplig tidskrift
2020

Third-generation biorefineries as the means to produce fuels and chemicals from CO2

Zihe Liu, Kai Wang, Yun Chen et al
Nature Catalysis. Vol. 3 (3), p. 274-288
Reviewartikel
2019

Metabolic engineering and transcriptomic analysis of Saccharomyces cerevisiae producing p-coumaric acid from xylose

Gheorghe M. Borja, A. Rodriguez, Kate Campbell et al
Microbial Cell Factories. Vol. 18 (1)
Artikel i vetenskaplig tidskrift
2019

Heterologous phosphoketolase expression redirects flux towards acetate, perturbs sugar phosphate pools and increases respiratory demand in Saccharomyces cerevisiae

Alexandra Linda Bergman, John Hellgren, Thomas Moritz et al
Microbial Cell Factories. Vol. 18 (1)
Artikel i vetenskaplig tidskrift
2019

Lipid engineering combined with systematic metabolic engineering of Saccharomyces cerevisiae for high-yield production of lycopene

Tian Ma, Bin Shi, Ziling Ye et al
Metabolic Engineering. Vol. 52, p. 134-142
Artikel i vetenskaplig tidskrift
2019

Harnessing xylose pathways for biofuels production

Xiaowei Li, Yun Chen, Jens Christian Froslev Nielsen
Current Opinion in Biotechnology. Vol. 57, p. 56-65
Reviewartikel
2019

Adaptive laboratory evolution of tolerance to dicarboxylic acids in Saccharomyces cerevisiae

Rui Pereira, Yongjun Wei, Elsayed Mohamed et al
Metabolic Engineering. Vol. 56, p. 130-141
Artikel i vetenskaplig tidskrift
2019

Rewiring carbon metabolism in yeast for high level production of aromatic chemicals

Quanli Liu, Tao Yu, Xiaowei Li et al
Nature Communications. Vol. 10 (1)
Artikel i vetenskaplig tidskrift
2019

Effects of overexpression of STB5 in Saccharomyces cerevisiae on fatty acid biosynthesis, physiology and transcriptome

Alexandra Linda Bergman, Dóra Vitay, John Hellgren et al
FEMS Yeast Research. Vol. 19 (3)
Artikel i vetenskaplig tidskrift
2019

Expanding the Dynamic Range of a Transcription Factor-Based Biosensor in Saccharomyces cerevisiae

Yasaman Dabirian, Xiaowei Li, Yun Chen et al
ACS Synthetic Biology. Vol. 8 (9), p. 1968-1975
Artikel i vetenskaplig tidskrift
2018

Global rewiring of cellular metabolism renders Saccharomyces cerevisiae Crabtree negative

Zongijie Dai, Mingtao Huang, Yun Chen et al
Nature Communications. Vol. 9 (1)
Artikel i vetenskaplig tidskrift
2018

Modular Pathway Rewiring of Yeast for Amino Acid Production

Quanli Liu, Tao Yu, Kate Campbell et al
Methods in Enzymology. Vol. 608, p. 417-439
Kapitel i bok
2017

Comparison of the metabolic response to over-production of p-coumaric acid in two yeast strains

A. Rodriguez, Yun Chen, Sakda Khoomrung et al
Metabolic Engineering. Vol. 44, p. 265-272
Artikel i vetenskaplig tidskrift
2017

Elimination of the last reactions in ergosterol biosynthesis alters the resistance of Saccharomyces cerevisiae to multiple stresses

Guodong Liu, Yun Chen, N. J. Faergeman et al
FEMS Yeast Research. Vol. 17 (6)
Artikel i vetenskaplig tidskrift
2017

Effects of acetoacetyl-CoA synthase expression on production of farnesene in Saccharomyces cerevisiae

Stefan Tippmann, Raphael Ferreira, Verena Siewers et al
Journal of Industrial Microbiology and Biotechnology. Vol. 44 (6), p. 911-922
Artikel i vetenskaplig tidskrift
2016

Thermotolerant yeasts selected by adaptive evolution express heat stress response at 30 degrees C

Luis Caspeta-Guadarrama, Yun Chen, Jens B Nielsen
Scientific Reports. Vol. 6, p. Art. no. 27003-
Artikel i vetenskaplig tidskrift
2016

Functional expression and evaluation of heterologous phosphoketolases in Saccharomyces cerevisiae

Alexandra Linda Bergman, Verena Siewers, Jens B Nielsen et al
AMB Express. Vol. 6 (1)
Artikel i vetenskaplig tidskrift
2016

Biobased organic acids production by metabolically engineered microorganisms

Yun Chen, Jens B Nielsen
Current Opinion in Biotechnology. Vol. 37, p. 165-172
Reviewartikel
2016

Engineering and systems-level analysis of Saccharomyces cerevisiae for production of 3-hydroxypropionic acid via malonyl-CoA reductase-dependent pathway

K. R. Kildegaard, N. B. Jensen, K. Schneider et al
Microbial Cell Factories. Vol. 15 (1)
Artikel i vetenskaplig tidskrift
2015

Ach1 is involved in shuttling mitochondrial acetyl units for cytosolic C2 provision in Saccharomyces cerevisiae lacking pyruvate decarboxylase

Yun Chen, Yiming Zhang, Verena Siewers et al
FEMS Yeast Research. Vol. 15 (3), p. 1-8
Artikel i vetenskaplig tidskrift
2015

Adaptive mutations in sugar metabolism restore growth on glucose in a pyruvate decarboxylase negative yeast strain

Yiming Zhang, Guodong Liu, Martin Engqvist et al
Microbial Cell Factories. Vol. 14 (116)
Artikel i vetenskaplig tidskrift
2015

Microbial acetyl-CoA metabolism and metabolic engineering

Anastasia Krivoruchko, Yiming Zhang, Verena Siewers et al
Metabolic Engineering. Vol. 28, p. 28-42
Övrig text i vetenskaplig tidskrift
2015

Production of 3-hydroxypropionic acid from glucose and xylose by metabolically engineered Saccharomyces cerevisiae

K. R. Kildegaard, Zheng Wang, Yun Chen et al
Metabolic Engineering Communications. Vol. 2, p. 132-136
Artikel i vetenskaplig tidskrift
2015

De novo production of resveratrol from glucose or ethanol by engineered Saccharomyces cerevisiae

M. Li, K. R. Kildegaard, Yun Chen et al
Metabolic Engineering. Vol. 32, p. 1-11
Artikel i vetenskaplig tidskrift
2015

Enabling Technologies to Advance Microbial Isoprenoid Production

Yun Chen, Yongjin Zhou, Verena Siewers et al
Advances in Biochemical Engineering/Biotechnology. Vol. 148, p. 143-160
Artikel i vetenskaplig tidskrift
2015

Functional pyruvate formate lyase pathway expressed with two different electron donors in Saccharomyces cerevisiae at aerobic growth

Yiming Zhang, Zongijie Dai, Anastasia Krivoruchko et al
FEMS Yeast Research. Vol. 15 (4)
Artikel i vetenskaplig tidskrift
2014

Altered sterol composition renders yeast thermotolerant

Luis Caspeta-Guadarrama, Yun Chen, PAYAM GHIACI et al
Science. Vol. 346 (6205), p. 75-78
Artikel i vetenskaplig tidskrift
2014

Coupled incremental precursor and co-factor supply improves 3-hydroxypropionic acid production in Saccharomyces cerevisiae

Yun Chen, Jichen Bao, Il-Kwon Kim et al
Metabolic Engineering. Vol. 22, p. 104-109
Artikel i vetenskaplig tidskrift
2014

Improving Production of Malonyl Coenzyme A-Derived Metabolites by Abolishing Snf1-Dependent Regulation of Acc1

S. B. Shi, Yun Chen, Verena Siewers et al
mBio. Vol. 5 (3)
Artikel i vetenskaplig tidskrift
2013

Advances in metabolic pathway and strain engineering paving the way for sustainable production of chemical building blocks

Yun Chen, Jens B Nielsen
Current Opinion in Biotechnology. Vol. 24 (6), p. 956-972
Reviewartikel
2013

Improving biobutanol production in engineered Saccharomyces cerevisiae by manipulation of acetyl-CoA metabolism

Anastasia Krivoruchko, Cristina Serrano-Amatriain, Yun Chen et al
Journal of Industrial Microbiology and Biotechnology. Vol. 40 (9), p. 1051-1056
Artikel i vetenskaplig tidskrift
2013

From flavors and pharmaceuticals to advanced biofuels: Production of isoprenoids in Saccharomyces cerevisiae

Stefan Tippmann, Yun Chen, Verena Siewers et al
Biotechnology journal. Vol. 8 (12), p. 1435-1444
Reviewartikel
2013

Establishing a platform cell factory through engineering of yeast acetyl-CoA metabolism

Yun Chen, L. Daviet, M. Schalk et al
Metabolic Engineering. Vol. 15 (1), p. 48-54
Artikel i vetenskaplig tidskrift
2012

dynamic control of gene expression in saccharomyces cerevisiae engineered for the production of plant sesquiterpene alpha-santalene in a fed-batch mode

Gionata Scalcinati, Christoph Knuf, Siavash Partow et al
Metabolic Engineering. Vol. 14 (2), p. 91-103
Artikel i vetenskaplig tidskrift
2012

Profiling of Cytosolic and Peroxisomal Acetyl-CoA Metabolism in Saccharomyces cerevisiae

Yun Chen, Verena Siewers, Jens B Nielsen
PLoS ONE. Vol. 7 (8), p. e42475-
Artikel i vetenskaplig tidskrift
2012

Engineering of acetyl-CoA metabolism for the improved production of polyhydroxybutyrate in Saccharomyces cerevisiae

Kanokarn Kocharin, Yun Chen, Verena Siewers et al
AMB Express. Vol. 2 (1)
Artikel i vetenskaplig tidskrift
2012

Enhancing the copy number of episomal plasmids in Saccharomyces cerevisiae for improved protein production

Yun Chen, Siavash Partow, Gionata Scalcinati et al
FEMS Yeast Research. Vol. 12 (5), p. 598-607
Artikel i vetenskaplig tidskrift
2011

Diversion of Flux toward Sesquiterpene Production in Saccharomyces cerevisiae by Fusion of Host and Heterologous Enzymes

L. Albertsen, Yun Chen, L. S. Bach et al
Applied and Environmental Microbiology. Vol. 77 (3), p. 1033-1040
Artikel i vetenskaplig tidskrift

Ladda ner publikationslistor

Du kan ladda ner denna lista till din dator.

Filtrera och ladda ner publikationslista

Som inloggad användare hittar du ytterligare funktioner i MyResearch.

Du kan även exportera direkt till Zotero eller Mendeley genom webbläsarplugins. Dessa hittar du här:

Zotero Connector
Mendeley Web Importer

Tjänsten SwePub erbjuder uttag av Researchs listor i andra format, till exempel kan du få uttag av publikationer enligt Harvard och Oxford i .RIS, BibTex och RefWorks-format.

Visar 10 forskningsprojekt

2023–2025

Direkt jäsningsväg för hållbara plaster och superabsorberande polymerer

Yun Chen Systembiologi
Formas

2 publikationer finns
2023–2025

Increasing oxygen utilisation in biotechnological processes

Yun Chen Systembiologi
Novo Nordisk Fonden

1 publikation finns
2020–2023

Microbial synthesis of medicinal natural products

Yun Chen Systembiologi
STINT

4 publikationer finns
2019–2021

Production of Benzylisoquinoline Alkaloids in Yeast

Jens B Nielsen Systembiologi
Yun Chen Systembiologi
Vetenskapsrådet (VR)

2 publikationer finns
2019–2021

Systems metabolic engineering of yeast for production of flavonoids

Yun Chen Systembiologi
Novo Nordisk Fonden

3 publikationer finns
2017–2019

Biosynthesis of the high-value plant secondary metabolites in yeast

Yun Chen Systembiologi
ÅForsk

2016–2017

Synthetic biochemical pathways for efficient conversion of xylose into renewable biofuels and chemicals

Yun Chen Systembiologi
Carl Tryggers Stiftelse för Vetenskaplig Forskning

Det kan finnas fler projekt där Yun Chen medverkar, men du måste vara inloggad som anställd på Chalmers för att kunna se dem.