Microwave-heated γ-Alumina Applied to the Reduction of Aldehydes to Alcohols
Artikel i vetenskaplig tidskrift, 2020

The development of cheap and robust heterogeneous catalysts for the Meerwein-Ponndorf-Verley (MPV) reduction is desirable due to the difficulties in product isolation and catalyst recovery associated with the traditional use of homogeneous catalysts for MPV. Herein, we show that microwave heated γ-Al2O3 can be used for the reduction of aldehydes to alcohols. The reaction is efficient and has a broad substrates scope (19 entries). The products can be isolated by simple filtration, and the catalyst can be regenerated. With the use of microwave heating, we can direct the heating to the catalyst rather than to the whole reaction medium. Furthermore, DFT was used to study the reaction mechanism, and we can conclude that a dual-site mechanism is operative where the aldehyde and 2-propoxide are situated on two adjacent Al sites during the reduction. Additionally, volcano plots were used to rationalize the reactivity of Al2O3 in comparison to other metal oxides.

Microwave-assisted catalysis

γ-Al O 2 3

MPV reduction

Författare

Bhausaheb Kashinath Dhokale

Chalmers, Kemi och kemiteknik, Kemi och biokemi

Arturo Susarrey- Arce

Chalmers, Fysik, Kemisk fysik

MESA Institute for Nanotechnology

Anna Pekkari

Chalmers, Kemi och kemiteknik, Tillämpad kemi, Farmaceutisk teknologi

August Runemark

Chalmers, Kemi och kemiteknik, Kemi och biokemi, Fysikalisk kemi

Kasper Moth-Poulsen

Chalmers, Kemi och kemiteknik, Tillämpad kemi, Kasper Moth-Poulsen Group

Christoph Langhammer

Chalmers, Fysik, Kemisk fysik

Hanna Härelind

Chalmers, Kemi och kemiteknik

Michael Busch

Aalto-Yliopisto

Matthias Vandichel

University of Limerick

Henrik Sundén

Chalmers, Kemi och kemiteknik, Kemi och biokemi

Göteborgs universitet

ChemCatChem

1867-3880 (ISSN) 1867-3899 (eISSN)

Vol. In Press

Ämneskategorier

Kemiska processer

Bioenergi

Organisk kemi

DOI

10.1002/cctc.202001284

Mer information

Senast uppdaterat

2020-11-09