Imaging the distribution of DMPBD and terpinen-4-ol inclusion complexes with 2-hydroxypropyl-beta-cyclodextrin by using TOF-SIMS
Artikel i vetenskaplig tidskrift, 2021

The distribution of terpinen-4-ol (TP4ol) and DMPBD inclusion complexes with 2-hydroxypropyl-beta-cyclodextrin (HPbCD) in human skin has been investigated using the TOF-SIMS technique. TP4ol and DMPBD have been found to be major components of Zingiber cassumunar Roxb. (Plai) oil extracted by steam distillation. The results mainly show accumulation of TP4ol and DMPBD inclusion complexes with HPbCD in the epidermis and dermis whereas these two compounds without cyclodextrin cannot penetrate into the epidermis. This approach can be expanded for investigation of anti-inflammatory action and relief of muscle pain.

Författare

Auraya Manaprasertsak

Kasetsart University

Per Malmberg

Chalmers, Kemi och kemiteknik, Kemi och biokemi

Theerachart Leepasert

Kasetsart University

Thitinun Karpkird

Kasetsart University

Analytical Methods

1759-9660 (ISSN) 1759-9679 (eISSN)

Vol. 13 1 84-89

Ämneskategorier

Analytisk kemi

Annan medicinsk grundvetenskap

Farmakologi och toxikologi

DOI

10.1039/d0ay02018d

PubMed

33300895

Mer information

Senast uppdaterat

2021-02-08