Neuromusculoskeletal interfacing of lower limb prostheses
Doktorsavhandling, 2021
The aim of this thesis has been to translate the concept of neuromusculoskeletal interfacing to the lower limb. An additional aim has been to reduce the limitations on high impact activities, that exist on current available systems for bone-anchored attachment of limb prostheses. To achieve these aims, a new design of the neuromusculoskeletal interface was developed where the structural capacity was increased with respect to current versions of the implant system to accommodate increased loads for highly active usage by individuals with lower limb amputation. In order to set adequate design requirements, investigations were conducted to determine the load exposure of bone-anchored implant systems during a number of loadbearing activities. Structural verification of the neuromusculoskeletal interface has been performed using numerical simulations as well as physical testing in static and dynamic conditions. The first steps towards clinical implementation of the lower limb neuromusculoskeletal interface have been taken by the development of a clinical research protocol that has been approved by the Swedish Ethical Review Authority.
OPRA
bone-anchored attachment
Enhanced Osseointegrated Prostheses for the Rehabilitation of Amputees (e-OPRA).
Osseointegration
direct skeletal attachment
neuromusculoskeletal interface
OPRA
Osseointegrated Prostheses for the Rehabilitation of Amputees (OPRA)
Enhanced Osseointegrated Prostheses for the Rehabilitation of Amputees (e-OPRA).
Författare
Alexander Thesleff
Chalmers, Elektroteknik, Signalbehandling och medicinsk teknik
Biomechanical Characterisation of Bone-anchored Implant Systems for Amputation Limb Prostheses: A Systematic Review
Annals of Biomedical Engineering,;Vol. 46(2018)p. 377-391
Reviewartikel
Loads at the implant-prosthesis interface during free and aided ambulation in osseointegrated transfemoral prostheses
IEEE Transactions on Medical Robotics and Bionics,;Vol. 2(2020)p. 497-505
Artikel i vetenskaplig tidskrift
Load exposure of osseointegrated implants for transfemoral limb prosthesis during running
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS,;Vol. 2018-July(2018)p. 1743-1746
Paper i proceeding
The effect of cortical thickness and thread profile dimensions on stress and strain in bone-anchored implants for amputation prostheses
Journal of the Mechanical Behavior of Biomedical Materials,;Vol. 129(2022)
Artikel i vetenskaplig tidskrift
Low plasticity burnishing improves fretting fatigue resistance in bone-anchored implants for amputation prostheses
Medical Engineering and Physics,;Vol. 100(2022)
Artikel i vetenskaplig tidskrift
Design of a stepwise safety protocol for lower limb prosthetic risk management in a clinical investigation
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS,;(2021)p. 4600-4604
Paper i proceeding
To address this problem, an interface which provides a direct connection between a prosthesis and the skeleton, muscles, and nerves has been developed. The skeletal interface provides a stable and comfortable mechanical connection between the prosthesis and the residual limb. The muscular interface allows for the recording of bioelectric signals from the musculature within the residual limb. The signals can then be used to provide intuitive control of the prosthesis. The neural interface allows for the stimulation of peripheral nerves. Such stimulation can generate sensations which the user perceives as coming from the missing limb. Combined with external sensors placed on the prosthesis, neurostimulation can therefore be used to provide sensory feedback from the prosthesis back to the user.
In this thesis this interface has been redesigned for usage with lower limb prostheses. It is believed that this technology will allow for long-term, robust and intuitive control of lower limb prostheses using bioelectric signals and sensory feedback via neurostimulation. What is unique with this interface is that it will not be restricted to usage in controlled laboratory environments but may function equally well during everyday use in home environments. The interface therefore has a great potential of providing actual functional improvements in the daily life for its users and thereby reduce the disability associated with a lower limb amputation.
Tankestyrd benprotes
VINNOVA (2017-01471), 2017-06-01 -- 2018-05-31.
Neural styrning av benproteser
Stiftelsen för Strategisk forskning (SSF) (ID15-0089), 2016-01-01 -- 2020-12-31.
Neuromuskulär styrning av robotben
VINNOVA (2018-03235), 2018-11-26 -- 2020-10-31.
Styrkeområden
Hälsa och teknik
Ämneskategorier
Medicinska material och protesteknik
ISBN
978-91-7905-494-6
Doktorsavhandlingar vid Chalmers tekniska högskola. Ny serie: 4961
Utgivare
Chalmers
Opponent: Prof. Helen Huang, North Carolina State University & University of North Carolina at Chapel Hill Joint Department of Biomedical Engineering, North Carolina, USA