Microwave-heated γ-Alumina Applied to the Reduction of Aldehydes to Alcohols
Artikel i vetenskaplig tidskrift, 2020

The development of cheap and robust heterogeneous catalysts for the Meerwein-Ponndorf-Verley (MPV) reduction is desirable due to the difficulties in product isolation and catalyst recovery associated with the traditional use of homogeneous catalysts for MPV. Herein, we show that microwave heated γ-Al2O3 can be used for the reduction of aldehydes to alcohols. The reaction is efficient and has a broad substrates scope (19 entries). The products can be isolated by simple filtration, and the catalyst can be regenerated. With the use of microwave heating, we can direct the heating to the catalyst rather than to the whole reaction medium. Furthermore, DFT was used to study the reaction mechanism, and we can conclude that a dual-site mechanism is operative where the aldehyde and 2-propoxide are situated on two adjacent Al sites during the reduction. Additionally, volcano plots were used to rationalize the reactivity of Al2O3 in comparison to other metal oxides.

MPV reduction

γ-Al O 2 3

Microwave-assisted catalysis


Bhausaheb Kashinath Dhokale

Chalmers, Kemi och kemiteknik, Kemi och biokemi

Arturo Susarrey- Arce

Chalmers, Fysik, Kemisk fysik

MESA Institute for Nanotechnology

Anna Pekkari

Chalmers, Kemi och kemiteknik, Tillämpad kemi

August Runemark

Chalmers, Kemi och kemiteknik, Kemi och biokemi

Kasper Moth-Poulsen

Chalmers, Kemi och kemiteknik, Tillämpad kemi

Christoph Langhammer

Chalmers, Fysik, Kemisk fysik

Hanna Härelind

Chalmers, Kemi och kemiteknik

Michael Busch


Matthias Vandichel

University of Limerick

Henrik Sundén

Göteborgs universitet

Chalmers, Kemi och kemiteknik, Kemi och biokemi


1867-3880 (ISSN) 1867-3899 (eISSN)

Vol. 12 24 6344-6355

Single Particle Catalysis in Nanoreactors (SPCN)

Knut och Alice Wallenbergs Stiftelse (KAW2015.0057), 2016-01-01 -- 2020-12-31.


Nanovetenskap och nanoteknik


Kemiska processer

Annan fysik




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