Martin Adiels
Forskarassistent at
Mathematics
Showing 58 publications
2018
An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans
Adil Mardinoglu, Hao Wu, Elias Björnson et al
Cell Metabolism. Vol. 27 (3), p. 559-571.e5
Journal article
2017
Personal model-assisted identification of NAD(+) and glutathione metabolism as intervention target in NAFLD
Adil Mardinoglu, Elias Björnson, C. Zhang et al
Molecular Systems Biology. Vol. 13 (3)
Journal article
2016
Changes in Dietary Fat Intake and Projections for Coronary Heart Disease Mortality in Sweden: A Simulation Study
Lena Björck, Annika Rosengren, Anna Winkvist et al
PLoS ONE. Vol. 11 (8), p. e0160474-
Journal article
2016
Metabolic transformations of dietary polyphenols: comparison between in vitro colonic and hepatic models and in vivo urinary metabolites.
Claudia Vetrani, Angela A Rivellese, Giovanni Annuzzi et al
The Journal of nutritional biochemistry. Vol. 33, p. 111-8
Journal article
2016
Triglyceride-rich lipoprotein metabolism in women: roles of apoC-II and apoC-III
E. M. Ooi, D. C. Chan, L. Hodson et al
European Journal of Clinical Investigation. Vol. 46 (8), p. 730-736
Journal article
2016
Perilipin 5 is protective in the ischemic heart
Christina Drevinge, K. T. Dalen, M. N. Mannila et al
International Journal of Cardiology. Vol. 219, p. 446-454
Journal article
2016
ApoA-II HDL Catabolism and Its Relationships With the Kinetics of ApoA-I HDL and of VLDL1, in Abdominal Obesity.
Bruno Vergès, Martin Adiels, Jan Borén et al
The Journal of clinical endocrinology and metabolism. Vol. 101 (4), p. 1398-406
Journal article
2016
Targeting acid sphingomyelinase reduces cardiac ceramide accumulation in the post-ischemic heart
M. Klevstig, Marcus Ståhlman, Annika Lundqvist et al
Journal of Molecular and Cellular Cardiology. Vol. 93, p. 69-72
Journal article
2015
Model-Based Quantification of the Systemic Interplay between Glucose and Fatty Acids in the Postprandial State
F. L. P. Sips, E. Nyman, Martin Adiels et al
PLoS ONE. Vol. 10 (9), p. e0135665-
Journal article
2015
Prognostic Significance of Resting Heart Rate and Use of beta-Blockers in Atrial Fibrillation and Sinus Rhythm in Patients With Heart Failure and Reduced Ejection Fraction: Findings From the Swedish Heart Failure Registry
S. J. Li, U. Sartipy, L. H. Lund et al
Circulation. Heart failure. Vol. 8 (5), p. 871-9
Journal article
2015
Improved Estimation of Human Lipoprotein Kinetics with Mixed Effects Models
Martin Berglund, Martin Adiels, M. R. Taskinen et al
PLoS ONE. Vol. 10 (9), p. artikel nr e0138538-
Journal article
2015
Kinetic and Related Determinants of Plasma Triglyceride Concentration in Abdominal Obesity Multicenter Tracer Kinetic Study
Jan Borén, G. F. Watts, Martin Adiels et al
Arteriosclerosis, Thrombosis, and Vascular Biology. Vol. 35 (10), p. 2218-2224
Journal article
2015
Kinetic Studies to Elucidate Impaired Metabolism of Triglyceride-rich Lipoproteins in Humans.
Martin Adiels, Adil Mardinoglu, Marja-Riitta Taskinen et al
Frontiers in Physiology. Vol. 6 (NOV), p. 342-
Journal article
2015
Imaging of Intracellular and Extracellular ROS Levels in Atherosclerotic Mouse Aortas Ex Vivo: Effects of Lipid Lowering by Diet or Atorvastatin
Matias Ekstrand, Maria Gustafsson Trajkovska, Jeanna Perman Sundelin et al
PLoS ONE. Vol. 10 (6), p. Article Number: e0130898-
Journal article
2015
Menopausal Status and Abdominal Obesity Are Significant Determinants of Hepatic Lipid Metabolism in Women
L. Hodson, R. Banerjee, B. Rial et al
Journal of the American Heart Association. Vol. 4 (10)
Journal article
2014
Postprandial hypertriglyceridemia as a coronary risk factor.
Jan Borén, Niina Matikainen, Martin Adiels et al
Clinica chimica acta; international journal of clinical chemistry. Vol. 431, p. 131-42
Review article
2014
Interrelationships Between the Kinetics of VLDL Subspecies and HDL Catabolism in Abdominal Obesity: A Multicenter Tracer Kinetic Study
B. Verges, Martin Adiels, Jan Borén et al
Journal of Clinical Endocrinology and Metabolism. Vol. 99 (11), p. 4281-4290
Journal article
2014
Lipid metabolism in metabolic syndrome
Jan Borén, Martin Adiels
A Systems Biology Approach to Study Metabolic Syndrome, p. 157-170
Book chapter
2014
Inhibition of MAPK Hog1 Results in Increased Hsp104 Aggregate Formation Probably through Elevated Arsenite Influx into the Cells, an Approach with Numerous Potential Applications
Doryaneh Ahmadpour, Amin Abbaszadehbanaeiyan, Morten Grötli et al
American Journal of Molecular Biology. Vol. 4 (2), p. 59-71
Journal article
2014
Dietary Medium Chain Fatty Acid Supplementation Leads to Reduced VLDL Lipolysis and Uptake Rates in Comparison to Linoleic Acid Supplementation
D. B. van Schalkwijk, W. J. Pasman, H. F. J. Hendriks et al
PLoS ONE. Vol. 9 (7), p. artikel e100376-
Journal article
2014
Hepatic Lipogenesis and a Marker of Hepatic Lipid Oxidation, Predict Postprandial Responses of Triglyceride-rich Lipoproteins
N. Matikainen, Martin Adiels, S. Soderlund et al
Obesity. Vol. 22 (8), p. 1854-1859
Journal article
2013
Cardiac steatosis associates with visceral obesity in nondiabetic obese men.
Marit Granér, Reijo Siren, Kristofer Nyman et al
The Journal of clinical endocrinology and metabolism. Vol. 98 (3), p. 1189-97
Journal article
2013
A continuous-time adaptive particle filter for estimations under measurement time uncertainties with an application to a plasma-leucine mixed effects model.
Annette Krengel, Jan Hauth, Marja-Riitta Taskinen et al
BMC Systems Biology. Vol. 7 (8), p. 33 sidor-
Journal article
2013
Dyslipidemia, but not hyperglycemia and insulin resistance, is associated with marked alterations in the HDL lipidome in type 2 diabetic subjects in the DIWA cohort: Impact on small HDL particles
Marcus Ståhlman, Björn Fagerberg, Martin Adiels et al
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. Vol. 1831 (11), p. 1609-1617
Journal article
2013
Genetic Variation in SULF2 Is Associated with Postprandial Clearance of Triglyceride-Rich Remnant Particles and Triglyceride Levels in Healthy Subjects.
Niina Matikainen, Maria A Burza, Stefano Romeo et al
PLoS ONE. Vol. 8 (11), p. e79473-
Journal article
2012
Clinical dyslipidaemia is associated with changes in the lipid composition and inflammatory properties of apolipoprotein-B-containing lipoproteins from women with type 2 diabetes.
Marcus Ståhlman, H T Pham, Martin Adiels et al
Diabetologia. Vol. 55 (4), p. 1156-66
Journal article
2012
Paradoxical Lower Serum Triglyceride Levels and Higher Type 2 Diabetes Mellitus Susceptibility in Obese Individuals with the PNPLA3 148M Variant
C. N. A. Palmer, Cristina Maglio, Carlo Pirazzi et al
PLoS ONE. Vol. 7 (6)
Journal article
2012
Postprandial accumulation of chylomicrons and chylomicron remnants is determined by the clearance capacity.
Martin Adiels, Niina Matikainen, Jukka Westerbacka et al
Atherosclerosis. Vol. 222 (1), p. 222-8
Journal article
2012
Interleukin 15 Mediates Joint Destruction in Staphylococcus Aureus Arthritis
Louise Henningsson, Pernilla Jirholt, Yalda Rahpeymai Bogestål et al
Journal of Infectious Diseases. Vol. 206 (5), p. 687-696
Journal article
2012
PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals
Maria A Burza, Carlo Pirazzi, Cristina Maglio et al
Digestive and Liver Disease. Vol. 44 (12), p. 1037-1041
Journal article
2012
Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro
Carlo Pirazzi, Martin Adiels, Maria A Burza et al
Journal of Hepatology. Vol. 57 (6), p. 1276-1282
Journal article
2012
Investigations of a compartmental model for leucine kinetics using non-linear mixed effects models with ordinary and stochastic differential equations.
Martin Berglund, Mikael Sunnåker, Martin Adiels et al
Mathematical medicine and biology : a journal of the IMA. Vol. 29 (4), p. 361-384
Journal article
2012
Evaluation of macrophage-specific promoters using lentiviral delivery in mice.
Malin Levin, Ulf Lidberg, Pernilla Jirholt et al
Gene Therapy. Vol. 19 (11), p. 1041-7
Journal article
2011
Young women partition fatty acids towards ketone body production rather than VLDL-TAG synthesis, compared with young men.
Kyriakoula Marinou, Martin Adiels, Leanne Hodson et al
British Journal of Nutrition. Vol. 105 (6), p. 857-65
Journal article
2011
Kinetic Studies to Investigate Lipoprotein Metabolism.
Jan Borén, Marja-Riitta Taskinen, Martin Adiels
Journal of Internal Medicine. Vol. 271 (2), p. 166-173
Review article
2011
Dual metabolic defects are required to produce hypertriglyceridemia in obese subjects.
Marja-Riitta Taskinen, Martin Adiels, Jukka Westerbacka et al
Arteriosclerosis, Thrombosis, and Vascular Biology. Vol. 31 (9), p. 2144-50
Journal article
2010
Optimization of N-methyl-N-[tert-butyldimethylsilyl]trifluoroacetamide as a derivatization agent for determining isotopic enrichment of glycerol in very-low density lipoproteins.
Martin Adiels, Thomas Larsson, Pauline Sutton et al
Rapid Communications in Mass Spectrometry. Vol. 24 (5), p. 586-592
Journal article
2009
Nutritional systems biology modeling: from molecular mechanisms to physiology.
Albert A de Graaf, Andreas P Freidig, Baukje De Roos et al
PLoS Computational Biology. Vol. 5 (11), p. e1000554-
Review article
2009
The Lipid Droplet: a Dynamic Organelle, not only Involved in the Storage and Turnover of Lipids
Sven-Olof Olofsson, Pontus Boström, Jens O. Lagerstedt et al
Cellular Lipid Metabolism, p. 394-
Book chapter
2009
ApoCIII-Enriched LDL in Type 2 Diabetes Displays Altered Lipid Composition, Increased Susceptibility for Sphingomyelinase and Increased binding to Biglycan.
A Hiukka, Marcus Ståhlman, Camilla Pettersson et al
Diabetes. Vol. 58 (9), p. 2018-2026
Journal article
2009
BASELINE apoB-100 AND TRIGLYCERIDE KINETICS PREDICTS POSTPRANDIAL TRIGLYCERIDE AND apoB-48 ACCUMULATION IN CHYLOMICRON, VLDL1 AND VLDL2 FRACTIONS
Martin Adiels, Niina Matikainen, Jukka Westerbacka et al
XV International Symposium on Atherosclerosis
Conference poster
2009
Rekrytering av medicinare till forskning kräver tidigt engagemang. Amanuensprogram visar att tidig forskningsstart ger bättre resultat.
Jan Borén, Martin Adiels, Ylva Wickström et al
Läkartidningen. Vol. 106 (46), p. 3072-4
Journal article
2009
A brief review of lipoprotein metabolism
Martin Adiels, Sven-Olof Olofsson, Marja-Riitta Taskinen et al
Evidence-Based Management of Lipid Disorders, p. 350-
Book chapter
2008
A Matlab Toolbox for Nonlinear Mixed Effects Modeling – Illustrated with a Model for Lipoprotein Kinetics
Mikael Sunnåker, Martin Berglund, Bernt Wennberg et al
9th International Conference on Systems Biology
Conference poster
2008
ApoCIII-enriched LDL in type 2 diabetes displays altered lipid composition and increased susceptibility for sphingomyelinase
Anne Hiukka, Marcus Ståhlman, Camilla Pettersson et al
CHEMISTRY AND PHYSICS OF LIPIDS. Vol. 154, p. 13-13
Paper in proceedings
2008
Visceral Adiposity, Liver Fat, and Atherogenic Dyslipidemia
Marja-Riitta Taskinen, Martin Adiels, Jan Borén
Abdominal Obesity and the Endocannabinoid System: From Basic Aspects to Clinical Management of Related Cardiometabolic Risk, p. 265-
Book chapter
2008
Overproduction of very low-density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome.
Martin Adiels, Sven-Olof Olofsson, Marja-Riitta Taskinen et al
Arteriosclerosis, Thrombosis, and Vascular Biology. Vol. 28 (7), p. 1225-36
Review article
2008
Fatty liver, insulin resistance, and dyslipidemia.
Martin Adiels, Marja-Riitta Taskinen, Jan Borén
Current Diabetes Reports. Vol. 8 (1), p. 60-4
Review article
2007
Acute suppression of VLDL(1) secretion rate by insulin is associated with hepatic fat content and insulin resistance
Martin Adiels, J. Westerbacka, A. Soro-Paavonen et al
Diabetologia. Vol. 50 (11), p. 2356-2365
Journal article
2007
Liver Fat Influences both the Baseline Production- and the Acute Regulation of VLDL1 TG and apoB
Martin Adiels, Jukka Westerbacka, A. Soro-Paavonen et al
ATHEROSCLEROSIS SUPPLEMENTS. Vol. 8 (1), p. 2-2
Paper in proceedings
2007
Liver fat influences both the baseline production – and the acute regulation of VLDL1 triglycerides (TG) and apoB
Martin Adiels, Marja-Riitta Taskinen, Jan Borén
13rdAnnual Scandinavian Atherosclerosis Conference
Conference poster
2006
Diabetic dyslipidaemia
Martin Adiels, Sven-Olof Olofsson, M. R. Taskinen et al
Current Opinion in Lipidology. Vol. 17 (3), p. 238-46
Journal article
2006
Overproduction of large VLDL particles is driven by increased liver fat content in man
Martin Adiels, M. R. Taskinen, C. Packard et al
Diabetologia. Vol. 49 (4), p. 755-65
Journal article
2005
A new combined multicompartmental model for apolipoprotein B-100 and triglyceride metabolism in VLDL subfractions
Martin Adiels, C. Packard, M. J. Caslake et al
Journal of Lipid Research. Vol. 46 (1), p. 58-67
Journal article
2005
Overproduction of VLDL1 driven by hyperglycemia is a dominant feature of diabetic dyslipidemia
Martin Adiels, Jan Borén, M. J. Caslake et al
Arteriosclerosis, Thrombosis, and Vascular Biology. Vol. 25 (8), p. 1697-703
Journal article
2004
How does mutant proprotein convertase neural apoptosis-regulated convertase 1 induce autosomal dominant hypercholesterolemia?
Pernilla Jirholt, Martin Adiels, Jan Borén
Arteriosclerosis, Thrombosis, and Vascular Biology. Vol. 24 (8), p. 1334-6
Journal article
2002
A compartmental model for kinetics of Apolipoprotein B-100 and Triglycerides in VLDL_1 and VLDL_2 in normolipidemic subjects
Martin Adiels
Licentiate thesis
Showing 1 research projects
2014–2019
Hierarchical mixed effects modelling of dynamical systems
Bernt Wennberg
Mathematical Sciences
Martin Adiels
Mathematics
Philip Gerlee
Applied Mathematics and Statistics
Torbjörn Lundh
Applied Mathematics and Statistics
Swedish Foundation for Strategic Research (SSF)
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