Martin Adiels

Forskarassistent at Department of Mathematical Sciences, Mathematics

Projects

2014–2019

Hierarchical mixed effects modelling of dynamical systems

Bernt Wennberg Department of Mathematical Sciences
Martin Adiels Department of Mathematical Sciences, Mathematics
Philip Gerlee Department of Mathematical Sciences, Mathematics
Torbjörn Lundh Department of Mathematical Sciences, Mathematics
Swedish Foundation for Strategic Research (SSF)

There might be more projects where Martin Adiels participates, but you have to be logged in as a Chalmers employee to see them.

Publications

2016

Triglyceride-rich lipoprotein metabolism in women: roles of apoC-II and apoC-III

E. M. Ooi, D. C. Chan, L. Hodson et al
European Journal of Clinical Investigation. Vol. 46 (8), p. 730-736
Scientific journal article - peer reviewed
2016

Perilipin 5 is protective in the ischemic heart

Christina Drevinge, K. T. Dalen, M. N. Mannila et al
International Journal of Cardiology. Vol. 219, p. 446-454
Scientific journal article - peer reviewed
2016

Targeting acid sphingomyelinase reduces cardiac ceramide accumulation in the post-ischemic heart

Martina Klevstig, Marcus Ståhlman, Annika Lundqvist et al
Journal of Molecular and Cellular Cardiology. Vol. 93, p. 69-72
Scientific journal article - peer reviewed
2016

Changes in Dietary Fat Intake and Projections for Coronary Heart Disease Mortality in Sweden: A Simulation Study

Lena Björck, Annika Rosengren, Anna Winkvist et al
PloS one. Vol. 11 (8), p. e0160474
Scientific journal article - peer reviewed
2016

ApoA-II HDL Catabolism and Its Relationships With the Kinetics of ApoA-I HDL and of VLDL1, in Abdominal Obesity.

Bruno Vergès, Martin Adiels, Jan Borén et al
The Journal of clinical endocrinology and metabolism. Vol. 101 (4), p. 1398-406
Scientific journal article - peer reviewed
2016

Metabolic transformations of dietary polyphenols: comparison between in vitro colonic and hepatic models and in vivo urinary metabolites.

Claudia Vetrani, Angela A Rivellese, Giovanni Annuzzi et al
The Journal of nutritional biochemistry. Vol. 33, p. 111-8
Scientific journal article - peer reviewed
2015

Kinetic Studies to Elucidate Impaired Metabolism of Triglyceride-rich Lipoproteins in Humans.

Martin Adiels, Adil Mardinoglu, Marja-Riitta Taskinen et al
Frontiers in Physiology. Vol. 6, p. 342
Scientific journal article - peer reviewed
2015

Menopausal Status and Abdominal Obesity Are Significant Determinants of Hepatic Lipid Metabolism in Women

L. Hodson, R. Banerjee, B. Rial et al
Journal of the American Heart Association. Vol. 4 (10)
Scientific journal article - peer reviewed
2015

Improved Estimation of Human Lipoprotein Kinetics with Mixed Effects Models

Martin Berglund, Martin Adiels, M. R. Taskinen et al
PLoS ONE. Vol. 10 (9), p. artikel nr e0138538
Scientific journal article - peer reviewed
2015

Kinetic and Related Determinants of Plasma Triglyceride Concentration in Abdominal Obesity Multicenter Tracer Kinetic Study

Jan Borén, G. F. Watts, Martin Adiels et al
Arteriosclerosis Thrombosis and Vascular Biology. Vol. 35 (10), p. 2218-2224
Scientific journal article - peer reviewed
2015

Model-Based Quantification of the Systemic Interplay between Glucose and Fatty Acids in the Postprandial State

F. L. P. Sips, E. Nyman, Martin Adiels et al
Plos One. Vol. 10 (9), p. e0135665
Scientific journal article - peer reviewed
2015

Imaging of Intracellular and Extracellular ROS Levels in Atherosclerotic Mouse Aortas Ex Vivo: Effects of Lipid Lowering by Diet or Atorvastatin

Matias Ekstrand, Maria Gustafsson Trajkovska, Jeanna Perman Sundelin et al
Plos One. Vol. 10 (6), p. Article Number: e0130898
Scientific journal article - peer reviewed
2014

Lipid metabolism in metabolic syndrome

Jan Borén, Martin Adiels,
A Systems Biology Approach to Study Metabolic Syndrome, p. 157-170
Chapter in monograph, book
2014

Interrelationships Between the Kinetics of VLDL Subspecies and HDL Catabolism in Abdominal Obesity: A Multicenter Tracer Kinetic Study

B. Verges, Martin Adiels, Jan Borén et al
Journal of Clinical Endocrinology & Metabolism. Vol. 99 (11), p. 4281-4290
Scientific journal article - peer reviewed
2014

Hepatic Lipogenesis and a Marker of Hepatic Lipid Oxidation, Predict Postprandial Responses of Triglyceride-rich Lipoproteins

N. Matikainen, Martin Adiels, S. Soderlund et al
Obesity. Vol. 22 (8), p. 1854-1859
Scientific journal article - peer reviewed
2014

Dietary Medium Chain Fatty Acid Supplementation Leads to Reduced VLDL Lipolysis and Uptake Rates in Comparison to Linoleic Acid Supplementation

D. B. van Schalkwijk, W. J. Pasman, H. F. J. Hendriks et al
PLoS ONE. Vol. 9 (7), p. artikel e100376
Scientific journal article - peer reviewed
2014

Postprandial hypertriglyceridemia as a coronary risk factor.

Jan Borén, Niina Matikainen, Martin Adiels et al
Clinica chimica acta; international journal of clinical chemistry. Vol. 431, p. 131-42
Scientific journal article - review article
2014

Inhibition of MAPK Hog1 Results in Increased Hsp104 Aggregate Formation Probably through Elevated Arsenite Influx into the Cells, an Approach with Numerous Potential Applications

Doryaneh Ahmadpour, Amin Abbaszadehbanaeiyan, Morten Grøtli et al
American Journal of Molecular Biology. Vol. 4 (2), p. 59-71
Scientific journal article - peer reviewed
2013

Genetic Variation in SULF2 Is Associated with Postprandial Clearance of Triglyceride-Rich Remnant Particles and Triglyceride Levels in Healthy Subjects.

Niina Matikainen, Maria A Burza, Stefano Romeo et al
PloS one. Vol. 8 (11), p. e79473
Scientific journal article - peer reviewed
2013

Dyslipidemia, but not hyperglycemia and insulin resistance, is associated with marked alterations in the HDL lipidome in type 2 diabetic subjects in the DIWA cohort: Impact on small HDL particles

Marcus Ståhlman, Björn Fagerberg, Martin Adiels et al
Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids. Vol. 1831 (11), p. 1609-1617
Scientific journal article - peer reviewed
2013

A continuous-time adaptive particle filter for estimations under measurement time uncertainties with an application to a plasma-leucine mixed effects model.

Annette Krengel, Jan Hauth, Marja-Riitta Taskinen et al
BMC systems biology. Vol. 7 (8), p. 33 sidor
Scientific journal article - peer reviewed
2013

Cardiac steatosis associates with visceral obesity in nondiabetic obese men.

Marit Granér, Reijo Siren, Kristofer Nyman et al
The Journal of clinical endocrinology and metabolism. Vol. 98 (3), p. 1189-97
Scientific journal article - peer reviewed
2012

Evaluation of macrophage-specific promoters using lentiviral delivery in mice.

Malin Levin, Ulf Lidberg, Pernilla Jirholt et al
Gene therapy. Vol. 19 (11), p. 1041-7
Scientific journal article - peer reviewed
2012

Clinical dyslipidaemia is associated with changes in the lipid composition and inflammatory properties of apolipoprotein-B-containing lipoproteins from women with type 2 diabetes.

Marcus Ståhlman, H T Pham, Martin Adiels et al
Diabetologia. Vol. 55 (4), p. 1156-66
Scientific journal article - peer reviewed
2012

Postprandial accumulation of chylomicrons and chylomicron remnants is determined by the clearance capacity.

Martin Adiels, Niina Matikainen, Jukka Westerbacka et al
Atherosclerosis. Vol. 222 (1), p. 222-8
Scientific journal article - peer reviewed
2012

PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals

Maria A Burza, Carlo Pirazzi, Cristina Maglio et al
Digestive and Liver Disease. Vol. 44 (12), p. 1037-1041
Scientific journal article - peer reviewed
2012

Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro

Carlo Pirazzi, Martin Adiels, Maria A Burza et al
Journal of Hepatology. Vol. 57 (6), p. 1276-1282
Scientific journal article - peer reviewed
2012

Interleukin 15 Mediates Joint Destruction in Staphylococcus Aureus Arthritis

Louise Henningsson, Pernilla Jirholt, Yalda Rahpeymai Bogestål et al
Journal of Infectious Diseases. Vol. 206 (5), p. 687-696
Scientific journal article - peer reviewed
2012

Paradoxical Lower Serum Triglyceride Levels and Higher Type 2 Diabetes Mellitus Susceptibility in Obese Individuals with the PNPLA3 148M Variant

C. N. A. Palmer, Cristina Maglio, Carlo Pirazzi et al
PLoS ONE. Vol. 7 (6)
Scientific journal article - peer reviewed
2012

Investigations of a compartmental model for leucine kinetics using non-linear mixed effects models with ordinary and stochastic differential equations.

Martin Berglund, Mikael Sunnåker, Martin Adiels et al
Mathematical medicine and biology : a journal of the IMA. Vol. 29 (4), p. 361-384
Scientific journal article - peer reviewed
2011

Kinetic Studies to Investigate Lipoprotein Metabolism.

Jan Borén, Marja-Riitta Taskinen, Martin Adiels et al
Journal of internal medicine. Vol. 271 (2), p. 166-173
Scientific journal article - review article
2011

Dual metabolic defects are required to produce hypertriglyceridemia in obese subjects.

Marja-Riitta Taskinen, Martin Adiels, Jukka Westerbacka et al
Arteriosclerosis, thrombosis, and vascular biology. Vol. 31 (9), p. 2144-50
Scientific journal article - peer reviewed
2011

Young women partition fatty acids towards ketone body production rather than VLDL-TAG synthesis, compared with young men.

Kyriakoula Marinou, Martin Adiels, Leanne Hodson et al
The British journal of nutrition. Vol. 105 (6), p. 857-65
Scientific journal article - peer reviewed
2010

Optimization of N-methyl-N-[tert-butyldimethylsilyl]trifluoroacetamide as a derivatization agent for determining isotopic enrichment of glycerol in very-low density lipoproteins.

Martin Adiels, Thomas Larsson, Pauline Sutton et al
Rapid communications in mass spectrometry : RCM. Vol. 24 (5), p. 586-592
Scientific journal article - peer reviewed
2009

BASELINE apoB-100 AND TRIGLYCERIDE KINETICS PREDICTS POSTPRANDIAL TRIGLYCERIDE AND apoB-48 ACCUMULATION IN CHYLOMICRON, VLDL1 AND VLDL2 FRACTIONS

Martin Adiels, Niina Matikainen, Jukka Westerbacka et al
XV International Symposium on Atherosclerosis
Conference poster
2009

Rekrytering av medicinare till forskning kräver tidigt engagemang. Amanuensprogram visar att tidig forskningsstart ger bättre resultat.

Jan Borén, Martin Adiels, Ylva Wickström et al
Läkartidningen. Vol. 106 (46), p. 3072-4
Scientific journal article - peer reviewed
2009

The Lipid Droplet: a Dynamic Organelle, not only Involved in the Storage and Turnover of Lipids

Sven-Olof Olofsson, Pontus Boström, Jens O. Lagerstedt et al
Cellular Lipid Metabolism, p. 394
Chapter in monograph, book
2009

A brief review of lipoprotein metabolism

Martin Adiels, Sven-Olof Olofsson, Marja-Riitta Taskinen et al
Evidence-Based Management of Lipid Disorders, p. 350
Chapter in monograph, book
2009

Nutritional systems biology modeling: from molecular mechanisms to physiology.

Albert A de Graaf, Andreas P Freidig, Baukje De Roos et al
PLoS computational biology. Vol. 5 (11), p. e1000554
Scientific journal article - review article
2009

ApoCIII-Enriched LDL in Type 2 Diabetes Displays Altered Lipid Composition, Increased Susceptibility for Sphingomyelinase and Increased binding to Biglycan.

A Hiukka, Marcus Ståhlman, Camilla Pettersson et al
Diabetes. Vol. 58 (9), p. 2018-2026
Scientific journal article - peer reviewed
2008

A Matlab Toolbox for Nonlinear Mixed Effects Modeling – Illustrated with a Model for Lipoprotein Kinetics

Mikael Sunnåker, Martin Berglund, Bernt Wennberg et al
9th International Conference on Systems Biology
Conference poster
2008

ApoCIII-enriched LDL in type 2 diabetes displays altered lipid composition and increased susceptibility for sphingomyelinase

Anne Hiukka, Marcus Ståhlman, Camilla Pettersson et al
CHEMISTRY AND PHYSICS OF LIPIDS. Vol. 154, p. 13-13
Conference paper - peer reviewed
2008

Visceral Adiposity, Liver Fat, and Atherogenic Dyslipidemia

Marja-Riitta Taskinen, Martin Adiels, Jan Borén et al
Abdominal Obesity and the Endocannabinoid System: From Basic Aspects to Clinical Management of Related Cardiometabolic Risk, p. 265
Chapter in monograph, book
2008

Fatty liver, insulin resistance, and dyslipidemia.

Martin Adiels, Marja-Riitta Taskinen, Jan Borén et al
Current diabetes reports. Vol. 8 (1), p. 60-4
Scientific journal article - review article
2008

Overproduction of very low-density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome.

Martin Adiels, Sven-Olof Olofsson, Marja-Riitta Taskinen et al
Arteriosclerosis, thrombosis, and vascular biology. Vol. 28 (7), p. 1225-36
Scientific journal article - review article
2007

Liver fat influences both the baseline production – and the acute regulation of VLDL1 triglycerides (TG) and apoB

Martin Adiels, Marja-Riitta Taskinen, Jan Borén et al
13rdAnnual Scandinavian Atherosclerosis Conference
Conference poster
2007

Liver Fat Influences both the Baseline Production- and the Acute Regulation of VLDL1 TG and apoB

Martin Adiels, Jukka Westerbacka, A. Soro-Paavonen et al
ATHEROSCLEROSIS SUPPLEMENTS. Vol. 8 (1), p. 2-2
Conference paper - peer reviewed
2007

Acute suppression of VLDL(1) secretion rate by insulin is associated with hepatic fat content and insulin resistance

Martin Adiels, J. Westerbacka, A. Soro-Paavonen et al
Diabetologia. Vol. 50 (11), p. 2356-2365
Scientific journal article - peer reviewed
2006

Overproduction of large VLDL particles is driven by increased liver fat content in man

Martin Adiels, M. R. Taskinen, C. Packard et al
Diabetologia. Vol. 49 (4), p. 755-65
Scientific journal article - peer reviewed
2006

Diabetic dyslipidaemia

Martin Adiels, Sven-Olof Olofsson, M. R. Taskinen et al
Curr Opin Lipidol. Vol. 17 (3), p. 238-46
Scientific journal article - peer reviewed
2005

A new combined multicompartmental model for apolipoprotein B-100 and triglyceride metabolism in VLDL subfractions

Martin Adiels, C. Packard, M. J. Caslake et al
J Lipid Res. Vol. 46 (1), p. 58-67
Scientific journal article - peer reviewed
2005

Overproduction of VLDL1 driven by hyperglycemia is a dominant feature of diabetic dyslipidemia

Martin Adiels, Jan Borén, M. J. Caslake et al
Arterioscler Thromb Vasc Biol. Vol. 25 (8), p. 1697-703
Scientific journal article - peer reviewed
2004

Compartmental models of lipoprotein kinetics

Martin Adiels,
Doctoral thesis
2004

How does mutant proprotein convertase neural apoptosis-regulated convertase 1 induce autosomal dominant hypercholesterolemia?

Pernilla Jirholt, Martin Adiels, Jan Borén et al
Arterioscler Thromb Vasc Biol. Vol. 24 (8), p. 1334-6
Scientific journal article - peer reviewed