Martin Adiels

An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans

2017

Personal model-assisted identification of NAD(+) and glutathione metabolism as intervention target in NAFLD

Changes in Dietary Fat Intake and Projections for Coronary Heart Disease Mortality in Sweden: A Simulation Study

Metabolic transformations of dietary polyphenols: comparison between in vitro colonic and hepatic models and in vivo urinary metabolites.

Triglyceride-rich lipoprotein metabolism in women: roles of apoC-II and apoC-III

Perilipin 5 is protective in the ischemic heart

ApoA-II HDL Catabolism and Its Relationships With the Kinetics of ApoA-I HDL and of VLDL1, in Abdominal Obesity.

Targeting acid sphingomyelinase reduces cardiac ceramide accumulation in the post-ischemic heart

Model-Based Quantification of the Systemic Interplay between Glucose and Fatty Acids in the Postprandial State

Prognostic Significance of Resting Heart Rate and Use of beta-Blockers in Atrial Fibrillation and Sinus Rhythm in Patients With Heart Failure and Reduced Ejection Fraction: Findings From the Swedish Heart Failure Registry

2015

Improved Estimation of Human Lipoprotein Kinetics with Mixed Effects Models

Kinetic and Related Determinants of Plasma Triglyceride Concentration in Abdominal Obesity Multicenter Tracer Kinetic Study

2015

Kinetic Studies to Elucidate Impaired Metabolism of Triglyceride-rich Lipoproteins in Humans.

Imaging of Intracellular and Extracellular ROS Levels in Atherosclerotic Mouse Aortas Ex Vivo: Effects of Lipid Lowering by Diet or Atorvastatin

Menopausal Status and Abdominal Obesity Are Significant Determinants of Hepatic Lipid Metabolism in Women

Postprandial hypertriglyceridemia as a coronary risk factor.

2014

Interrelationships Between the Kinetics of VLDL Subspecies and HDL Catabolism in Abdominal Obesity: A Multicenter Tracer Kinetic Study

Lipid metabolism in metabolic syndrome

2014

Inhibition of MAPK Hog1 Results in Increased Hsp104 Aggregate Formation Probably through Elevated Arsenite Influx into the Cells, an Approach with Numerous Potential Applications

2014

Dietary Medium Chain Fatty Acid Supplementation Leads to Reduced VLDL Lipolysis and Uptake Rates in Comparison to Linoleic Acid Supplementation

Hepatic Lipogenesis and a Marker of Hepatic Lipid Oxidation, Predict Postprandial Responses of Triglyceride-rich Lipoproteins

2013

Cardiac steatosis associates with visceral obesity in nondiabetic obese men.

2013

A continuous-time adaptive particle filter for estimations under measurement time uncertainties with an application to a plasma-leucine mixed effects model.

Dyslipidemia, but not hyperglycemia and insulin resistance, is associated with marked alterations in the HDL lipidome in type 2 diabetic subjects in the DIWA cohort: Impact on small HDL particles

2013

Genetic Variation in SULF2 Is Associated with Postprandial Clearance of Triglyceride-Rich Remnant Particles and Triglyceride Levels in Healthy Subjects.

2012

Clinical dyslipidaemia is associated with changes in the lipid composition and inflammatory properties of apolipoprotein-B-containing lipoproteins from women with type 2 diabetes.

Paradoxical Lower Serum Triglyceride Levels and Higher Type 2 Diabetes Mellitus Susceptibility in Obese Individuals with the PNPLA3 148M Variant

Postprandial accumulation of chylomicrons and chylomicron remnants is determined by the clearance capacity.

Interleukin 15 Mediates Joint Destruction in Staphylococcus Aureus Arthritis

PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals

Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro

Investigations of a compartmental model for leucine kinetics using non-linear mixed effects models with ordinary and stochastic differential equations.

Evaluation of macrophage-specific promoters using lentiviral delivery in mice.

Young women partition fatty acids towards ketone body production rather than VLDL-TAG synthesis, compared with young men.

Kinetic Studies to Investigate Lipoprotein Metabolism.

Dual metabolic defects are required to produce hypertriglyceridemia in obese subjects.

Optimization of N-methyl-N-[tert-butyldimethylsilyl]trifluoroacetamide as a derivatization agent for determining isotopic enrichment of glycerol in very-low density lipoproteins.

Nutritional systems biology modeling: from molecular mechanisms to physiology.

The Lipid Droplet: a Dynamic Organelle, not only Involved in the Storage and Turnover of Lipids

ApoCIII-Enriched LDL in Type 2 Diabetes Displays Altered Lipid Composition, Increased Susceptibility for Sphingomyelinase and Increased binding to Biglycan.

BASELINE apoB-100 AND TRIGLYCERIDE KINETICS PREDICTS POSTPRANDIAL TRIGLYCERIDE AND apoB-48 ACCUMULATION IN CHYLOMICRON, VLDL1 AND VLDL2 FRACTIONS

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A brief review of lipoprotein metabolism

A Matlab Toolbox for Nonlinear Mixed Effects Modeling – Illustrated with a Model for Lipoprotein Kinetics

ApoCIII-enriched LDL in type 2 diabetes displays altered lipid composition and increased susceptibility for sphingomyelinase

Visceral Adiposity, Liver Fat, and Atherogenic Dyslipidemia

Overproduction of very low-density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome.

Fatty liver, insulin resistance, and dyslipidemia.

Acute suppression of VLDL(1) secretion rate by insulin is associated with hepatic fat content and insulin resistance

Liver Fat Influences both the Baseline Production- and the Acute Regulation of VLDL1 TG and apoB

Liver fat influences both the baseline production – and the acute regulation of VLDL1 triglycerides (TG) and apoB

Diabetic dyslipidaemia

Overproduction of large VLDL particles is driven by increased liver fat content in man

A new combined multicompartmental model for apolipoprotein B-100 and triglyceride metabolism in VLDL subfractions

Overproduction of VLDL1 driven by hyperglycemia is a dominant feature of diabetic dyslipidemia

How does mutant proprotein convertase neural apoptosis-regulated convertase 1 induce autosomal dominant hypercholesterolemia?

Compartmental models of lipoprotein kinetics

2002

A compartmental model for kinetics of Apolipoprotein B-100 and Triglycerides in VLDL_1 and VLDL_2 in normolipidemic subjects