Personal model-assisted identification of NAD(+) and glutathione metabolism as intervention target in NAFLD
Journal article, 2017
genome-scale
hepatocellular-carcinoma
muscle
personalized genome-scale metabolic modeling
tissue blood-flow
amino-acid-metabolism
serine
insulin-resistance
drug targets
glutathione
adipose-tissue
fatty liver-disease
NAFLD
obesity
Author
Adil Mardinoglu
Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology
Elias Björnson
Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology
C. Zhang
Royal Institute of Technology (KTH)
M. Klevstig
Sahlgrenska University Hospital
S. Soderlund
Helsinki University Central Hospital
Marcus Ståhlman
Sahlgrenska University Hospital
Martin Adiels
Sahlgrenska University Hospital
A. Hakkarainen
Helsinki University Central Hospital
N. Lundbom
Helsinki University Central Hospital
M. Kilicarslan
University of Amsterdam
B. M. Hallstrom
Royal Institute of Technology (KTH)
J. Lundbom
Helsinki University Central Hospital
B. Verges
Centre Hospitalier Universitaire de Dijon
P. H. R. Barrett
University of Western Australia
G. F. Watts
University of Western Australia
M. J. Serlie
University of Amsterdam
Jens B Nielsen
Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology
M. Uhlen
Royal Institute of Technology (KTH)
U. Smith
Sahlgrenska University Hospital
H. U. Marschall
Sahlgrenska University Hospital
M. R. Taskinen
Helsinki University Central Hospital
Jan Borén
Sahlgrenska University Hospital
Molecular Systems Biology
17444292 (eISSN)
Vol. 13 3 916Subject Categories
Pharmaceutical Sciences
Biomedical Laboratory Science/Technology
Pharmacology and Toxicology
DOI
10.15252/msb.20167422