Cecilia Tullberg is a Ph.D. student in the marine research group, working with oxidation of marine long-chain n-3 polyunsaturated fatty acids (LC n-3 PUFA, also called omega-3 fatty acids) during digestion. The main focus of this project lies on understanding what happens with marine omega-3 fatty acids in the gastrointestinal tract, using digestive juices of human origin. A high omega-3 intake has been connected with reduced risk of many unwanted diseases, such as cardiovascular and inflammatory diseases. However, meta-analyses have shown contradictory results, indicating that certain factors may interfere with the beneficial effects of marine omega-3 fatty acids. One of these interfering factors could be the high susceptibility of omega-3 fatty acids to oxidation and the following generation of reactive oxidation products, such as aldehydes. In vitro studies using digestive enzymes of porcine origin have previously shown that marine omega-3 can oxidize, and that oxidation products can be formed, under gastrointestinal tract conditions. With this project we aim to get a deeper understanding of lipid oxidation that takes place when marine lipids are transported through the digestive system and how this affects surrounding cells.