Alexandra Stubelius

Associate Professor at Chemical Biology

The overall goal of Alexandra Stubelius’ research is to reshape and remodel the immunesystem to reduce inflammation and restore tissue function. This is achieved through advanced nanotherapeutics and specifcally designed biomaterials. She holds a PhD in Medicine, specialized in inflammation and rheumatology, a MSc in Pharmacy and Pharmaceutical Biosciences and did a postdoc in nanomedicine at the University of California, San Diego.

At Chalmers, she sits in the steering committee of the Area of Advance Nano, and is also active in the Area of Advance Health Engineering as well as Area of Advance Materials Science.

 

For her interests in developing novel therapeutic approaches, she is sits on the board of the Controlled Release Society Nordic Local Chapter, and she is highly involved in the Nordic University Consortium NordicPOP (patient oriented products) and its continuation NordicPharmaTrain, both focusing on Nordic academic and industrial Collaborations to strengthen Nordic Drug Delivery Research.

 

For her interest in joint diseases, she is involved in the EU-funded network NetwOArk, with a mission to set up a European Society for Osteoarthritis.

 

Since 2024, she is also the Director of the Master Program in Biotechnology at Chalmers, and teaches pharmaceutical technologies for pharmacy students at the University of Gothenburg.

Source: chalmers.se
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Showing 15 publications

2024

CATIONIC NANOPARTICLES MODULATE ELECTROSTATIC INTERACTIONS IN CATABOLIC CARTILAGE

Ula von Mentzer, Fritjof Havemeister, Loise Råberg et al
Osteoarthritis and Cartilage. Vol. 32, p. S304-S304
Other conference contribution
2024

Nature inspired unique antimicrobial peptides from Chilean marine sediments

Luisa Beyer, Ann-Britt Schäfer, Agustina Natalia Undabarrena Canusso et al
Journal of Peptide Science. Vol. 30 (2)
Other text in scientific journal
2024

Achieving Precision Healthcare through Nanomedicine and Enhanced Model Systems

Elin Svensson, Ula von Mentzer, Alexandra Stubelius
ACS Materials Au. Vol. 4 (2), p. 162-173
Review article
2024

Dynamic Release from Acetalated Dextran Nanoparticles for Precision Therapy of Inflammation

Gizem Erensoy, Loise Råberg, Ula von Mentzer et al
ACS Applied Bio Materials. Vol. 7
Journal article
2024

Mimicking Nonribosomal Peptides from the Marine Actinomycete Streptomyces sp. H-KF8 Leads to Antimicrobial Peptides

Luisa I. Beyer, Ann-Britt Schäfer, Agustina Undabarrena et al
ACS Infectious Diseases. Vol. 10 (1), p. 79-92
Journal article
2024

A NANOPARTICLE-BASED PLATFORM TO DELINEATE BIOCHEMICAL MECHANISMS OF CATABOLIC DEGRADATION IN OSTEOARTHRITIS

Ula von Mentzer, Elin Svensson, Ruslan Ryskulov et al
Osteoarthritis and Cartilage. Vol. 32 (Supplement 1), p. S289-S290
Other conference contribution
2024

PAIN IN OSTEOARTHRITIS MICE: OVARIAN HORMONES REGULATE THE RESPONSE OF A2B ADENOSINE RECEPTORS

Sofia Wustenhagen, Julia M. Scheffler, Loise Råberg et al
Osteoarthritis and Cartilage. Vol. 32 (Supplement 1), p. S513-S513
Other conference contribution
2022

Theranostic Agent Combining Fullerene Nanocrystals and Gold Nanoparticles for Photoacoustic Imaging and Photothermal Therapy

Riku Kawasaki, Kosuke Kondo, Risako Miura et al
International Journal of Molecular Sciences. Vol. 23 (9)
Journal article
2022

Physiological levels of estradiol limit murine osteoarthritis progression

Carmen Corciulo, Julia M. Scheffler, Piotr Humeniuk et al
The Journal of endocrinology. Vol. 255 (2), p. 39-51
Journal article
2022

Synovial fluid profile dictates nanoparticle uptake into cartilage - implications of the protein corona for novel arthritis treatments

Ula von Mentzer, Tilia Selldén, Loise Råberg et al
Osteoarthritis and Cartilage. Vol. 30 (10), p. 1356-1364
Journal article
2022

A PHYSIOLOGICAL DOSE OF ESTRADIOL IN A MURINE OSTEOARTHRITIS MODEL PARTIALLY RESCUES THE PHENOTYPE OF THE HEALTHY JOINT

C. Corciulo, J. M. Scheffler, P. Humeniuk et al
Osteoarthritis and Cartilage. Vol. 30, p. S301-S302
Other conference contribution
2022

Biomaterial Integration in the Joint: Pathological Considerations, Immunomodulation, and the Extracellular Matrix

Ula von Mentzer, Carmen Corciulo, Alexandra Stubelius
Macromolecular Bioscience. Vol. 22 (7)
Review article
2020

Highly responsive and rapid hydrogen peroxide-triggered degradation of polycaprolactone nanoparticles

Peng-Hao Hsu, Carina Arboleda, Alexandra Stubelius et al
Biomaterials Science. Vol. 8 (9), p. 2394-2397
Journal article
2020

Androgen Receptors in Epithelial Cells Regulate Thymopoiesis and Recent Thymic Emigrants in Male Mice

Anna S. Wilhelmson, Marta Lantero Rodriguez, Inger Johansson et al
Frontiers in Immunology. Vol. 11
Journal article
2019

The Chemistry of Boronic Acids in Nanomaterials for Drug Delivery

Alexandra Stubelius, Sangeun Lee, Adah Almutairi
Accounts of Chemical Research. Vol. 52 (11), p. 3108-3119
Review article

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Showing 5 research projects

2022–2026

Enhancing Treatment Strategies for Osteoarthritis: Targeting Microenvironmental Proinflammatory Sialic Acid Signaling

Alexandra Stubelius Chemical Biology
Harald och Greta Jeanssons Stiftelse
Swedish Research Council (VR)

2021–2023

Precision Medicine for Rheumatoid Arhtritis: Utilizing Disease Mechanisms to Achieve Self-Adjusting Nanotherapeutics

Alexandra Stubelius Chemical Biology
Stiftelsen Anna-Greta och Holger Crafoords fond

1 publication exists
2020–2021

Nanocarriers Regulating Metabolism as a NovelTreatment Strategy for Age-Induced Osteoarthritis

Alexandra Stubelius Chemical Biology
Stiftelsen Sigurd och Elsa Goljes Minne

2020–2023

Bioresponsive nanomaterials to improve drug-delivery in Rheumatoid Arthritis

Alexandra Stubelius Chemical Biology
King Gustaf V's 80-year foundation

2020–2023

Smart nanomedicin för inflammatorisk läkemedelsleverans

Alexandra Stubelius Chemical Biology
Apotekare Hedbergs fond för Medicinsk forskning

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