Genetic biosensors for developing better cell factories for production of platform chemicals

Efficient biochemical conversion of renewable carbon sources is crucial for the transition into a resource efficient society. Industrial processes require strains that are tolerant to several stress conditions and display a high productivity, features to be developed in order for biobased chemicals and materials to be price-competitive.


The aim of this project is to develop genetic biosensors for yeast, that report intracellular concentrations of biochemicals produced by the cells or inhibitors found in the raw material. Inhibitors are abundant in lignocellulosic hydrolysates, a raw material made from plant biomass unsuited for use as food. The biosensors developed can be used for finding more robust and efficient cell factories with increased tolerance or for screening strains with an increased production of biochemicals.

Participants

Yvonne Nygård (contact)

Forskarassistent vid Chalmers, Biology and Biological Engineering, Industrial Biotechnology

Lisbeth Olsson

Professor vid Chalmers, Biology and Biological Engineering, Industrial Biotechnology

Funding

Formas

Funding Chalmers participation during 2018–2020 with 3,000,000.00 SEK

Related Areas of Advance and Infrastructure

Sustainable development

Driving Forces

Energy

Areas of Advance

Life Science Engineering

Areas of Advance

More information

Latest update

2018-02-26