Identifying molecular effects of diet through systems biology: influence of herring diet on sterol metabolism and protein turnover in mice
Journal article, 2010
Changes in lifestyle have resulted in an epidemic development of obesity-related diseases that challenge the healthcare systems worldwide. To develop strategies to tackle this problem the focus is on diet to prevent the development of obesity-associated diseases such as cardiovascular disease (CVD). This will require methods for linking nutrient intake with specific metabolic processes in different tissues.
Diet
methods
Metabolic Networks and Pathways
metabolism
Systems Biology
Fishes
Adipocytes
metabolism
Animals
metabolism
Proteins
Male
Organ Specificity
Sterols
Phenotype
White
Gene Expression Profiling
Mice
Author
Intawat Nookaew
Chalmers, Chemical and Biological Engineering, Life Sciences
Britt Gabrielsson
University of Gothenburg
Agneta Holmäng
University of Gothenburg
Ann-Sofie Sandberg
Chalmers, Chemical and Biological Engineering, Life Sciences
Jens B Nielsen
Chalmers, Chemical and Biological Engineering, Life Sciences
PLoS ONE
1932-6203 (ISSN) 19326203 (eISSN)
Vol. 5 8 e12361- e12361Subject Categories
MEDICAL AND HEALTH SCIENCES
Chemical Sciences
Areas of Advance
Life Science Engineering (2010-2018)
DOI
10.1371/journal.pone.0012361
PubMed
20808764