Maternal Intake of Cow's Milk during Lactation Is Associated with Lower Prevalence of Food Allergy in Offspring
Journal article, 2020

Maternal diet during pregnancy and lactation may affect the propensity of the child to develop an allergy. The aim was to assess and compare the dietary intake of pregnant and lactating women, validate it with biomarkers, and to relate these data to physician-diagnosed allergy in the offspring at 12 months of age. Maternal diet during pregnancy and lactation was assessed by repeated semi-quantitative food frequency questionnaires in a prospective Swedish birth cohort (n = 508). Fatty acid proportions were measured in maternal breast milk and erythrocytes. Allergy was diagnosed at 12 months of age by a pediatrician specialized in allergy. An increased maternal intake of cow's milk during lactation, confirmed with biomarkers (fatty acids C15:0 and C17:0) in the maternal blood and breast milk, was associated with a lower prevalence of physician-diagnosed food allergy by 12 months of age. Intake of fruit and berries during lactation was associated with a higher prevalence of atopic eczema at 12 months of age. Our results suggest that maternal diet modulates the infant's immune system, thereby influencing subsequent allergy development.



atopic eczema

dietary biomarkers

food intake

food allergy



breast milk



Mia Stråvik

Chalmers, Biology and Biological Engineering, Food and Nutrition Science

Malin Barman

Chalmers, Biology and Biological Engineering, Food and Nutrition Science

Karolinska Institutet

Bill Hesselmar

University of Gothenburg

Anna Sandin

Umeå University

Agnes E Wold

University of Gothenburg

Ann-Sofie Sandberg

Chalmers, Biology and Biological Engineering, Food and Nutrition Science


2072-6643 (ISSN) 20726643 (eISSN)

Vol. 12 12 1-19 3680

The role of prenatal diet- and microbiome- derived metabolome in childhood allergy development. Metabolic fingerprinting for allergy prediction

Swedish Research Council (VR) (2019-01317), 2020-01-01 -- 2023-12-31.

Maternal nutrition during pregnancy and lactation in relation to allergy in childhood

The Royal Society of Arts and Sciences in Gothenburg (2019-323), 2019-08-01 -- 2020-06-30.

Stiftelsen Sigurd och Elsa Goljes Minne (LA2019-0105), 2019-04-01 -- 2020-03-31.

Stiftelsen Wilhelm och Martina Lundgrens Vetenskapsfond (LA2019-0105), 2019-05-01 -- 2020-04-30.

Magnus Bergvalls Stiftelse (2017-02297), 2018-01-15 -- 2020-01-15.

Mammans mat under graviditet och amning och allergi hos barnet

Jane and Dan Olssons Foundations (2020-23), 2020-05-20 -- 2021-04-30.

Kostens roll under graviditet, amning och småbarnstiden för prevention av allergi

Dr Per Håkanssons stiftelse (MalinBarmanKostensroll), 2019-05-20 -- 2020-09-30.

Subject Categories


Animal and Dairy Sience

Obstetrics, Gynecology and Reproductive Medicine

Nutrition and Dietetics





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