yApoptosis: yeast apoptosis database
Artikel i vetenskaplig tidskrift, 2013

In the past few years, programmed cell death (PCD) has become a popular research area due to its fundamental aspects and its links to human diseases. Yeast has been used as a model for studying PCD, since the discovery of morphological markers of apoptotic cell death in yeast in 1997. Increasing knowledge in identification of components and molecular pathways created a need for organization of information. To meet the demands from the research community, we have developed a curated yeast apoptosis database, yApoptosis. The database structurally collects an extensively curated set of apoptosis, PCD and related genes, their genomic information, supporting literature and relevant external links. A web interface including necessary functions is provided to access and download the data. In addition, we included several networks where the apoptosis genes or proteins are involved, and present them graphically and interactively to facilitate rapid visualization. We also promote continuous inputs and curation by experts. yApoptosis is a highly specific resource for sharing information online, which supports researches and studies in the field of yeast apoptosis and cell death.

SACCHAROMYCES-CEREVISIAE

COMPLEXES

GENOME

PROTEIN-INTERACTION NETWORKS

SYSTEMS BIOLOGY

PROGRAMMED CELL-DEATH

ATLAS

Författare

Kwanjeera Wanichthanarak

Chalmers, Kemi- och bioteknik, Livsvetenskaper, Systembiologi

Marija Cvijovic

Chalmers, Matematiska vetenskaper, Matematik

Göteborgs universitet

Andrea Molt

Chalmers, Kemi- och bioteknik

Dina Petranovic Nielsen

Chalmers, Kemi- och bioteknik, Livsvetenskaper, Systembiologi

Database : the journal of biological databases and curation

1758-0463 (ISSN)

Vol. 2013 Art. no. bat068

Industrial Systems Biology of Yeast and A. oryzae (INSYSBIO)

Europeiska kommissionen (FP7), 2010-01-01 -- 2014-12-31.

Ämneskategorier

Biokemi och molekylärbiologi

Bioinformatik och systembiologi

Styrkeområden

Livsvetenskaper och teknik

DOI

10.1093/database/bat068