Marija Cvijovic

Professor vid Tillämpad matematik och statistik

Forskningen fokuserar på systembiologi av åldrande och protein-folding sjukdomar. För att närma sig dessa problem utvecklar gruppen specialiserade dynamiska modeller kompletterat med experimentellt arbete. Målet är att förstå de mekanismer som leder till bildandet av protein-folding sjukdomar och avser biokemiska cellulära processer till ett hälsosamt åldrande och livslängd. I strävan efter dessa mål kommer viktig vetenskaplig information att vara tillgänglig för att hantera viktiga prioriteringar för folkhälsopolitiken i framtiden.

Mer info: www.cvijoviclab.org

Källa: chalmers.se

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Publikationer (44)
Projekt (0)

Visar 44 publikationer

2023

Network medicine: facilitating a new view on complex diseases

Marija Cvijovic, Annikka Polster

Frontiers in Bioinformatics. Vol. 3

Artikel i vetenskaplig tidskrift

2022

The Effect of Lithium on the Budding Yeast Saccharomyces cerevisiae upon Stress Adaptation

Patrick Philipp Reith, Svenja Braam, Niek Welkenhuysen et al

Microorganisms. Vol. 10 (3)

Artikel i vetenskaplig tidskrift

Visa projekt

2022

The effect of stress on biophysical characteristics of misfolded protein aggregates in living Saccharomyces cerevisiae cells

Barbara Maria Schnitzer, Niek Welkenhuysen, Mark C. Leake et al

Experimental Gerontology. Vol. 162

Reviewartikel

2022

Multi-scale model suggests the trade-off between protein and ATP demand as a driver of metabolic changes during yeast replicative ageing

Barbara Maria Schnitzer, Linnea Österberg, Iro Skopa et al

PLoS Computational Biology. Vol. 18 (7)

Artikel i vetenskaplig tidskrift

2022

Optimizing study design in LPS challenge studies for quantifying drug induced inhibition of TNFα response: Did we miss the prime time?

Julia Larsson, Edmund Hoppe, Michael Gautrois et al

European Journal of Pharmaceutical Sciences. Vol. 176

Artikel i vetenskaplig tidskrift

2022

Scalable and flexible inference framework for stochastic dynamic single-cell models

Sebastian Persson, Niek Welkenhuysen, Sviatlana Shashkova et al

PLoS Computational Biology

Artikel i vetenskaplig tidskrift

2022

The choice of the objective function in flux balance analysis is crucial for predicting replicative lifespans in yeast

Barbara Maria Schnitzer, Linnea Österberg, Marija Cvijovic

PLoS ONE. Vol. 17 (10), p. e0276112-

Artikel i vetenskaplig tidskrift

2022

Modelling of glucose repression signalling in yeast Saccharomyces cerevisiae

Sebastian Persson, Sviatlana Shashkova, Linnea Österberg et al

FEMS Yeast Research. Vol. 22 (1)

Reviewartikel

2021

Second-generation TNFα turnover model for improved analysis of test compound interventions in LPS challenge studies

Julia Larsson, Edmund Hoppe, Michael Gautrois et al

European Journal of Pharmaceutical Sciences. Vol. 165

Artikel i vetenskaplig tidskrift

2021

A novel stepwise integrative analysis pipeline reveals distinct microbiota-host interactions and link to symptoms in irritable bowel syndrome

A. Polster, Lena Öhman, Julien Tap et al

Scientific Reports. Vol. 11 (1)

Artikel i vetenskaplig tidskrift

2021

Cell polarisation in a bulk-surface model can be driven by both classic and non-classic Turing instability

Johannes Borgqvist, Adam Malik, Carl Lundholm et al

npj Systems Biology and Applications. Vol. 7 (1)

Artikel i vetenskaplig tidskrift

2021

A novel yeast hybrid modeling framework integrating Boolean and enzyme-constrained networks enables exploration of the interplay between signaling and metabolism

Linnea Österberg, Iván Domenzain Del Castillo Cerecer, Julia Münch et al

PLoS Computational Biology. Vol. 17 (4)

Artikel i vetenskaplig tidskrift

Visa projekt

2020

Synergistic effects of repair, resilience and retention of damage determine the conditions for replicative ageing

Johannes Borgqvist, Niek Welkenhuysen, Marija Cvijovic

Scientific Reports. Vol. 10 (1)

Artikel i vetenskaplig tidskrift

2020

Fine-Tuning of Energy Levels Regulates SUC2 via a SNF1-Dependent Feedback Loop

Sebastian Persson, Niek Welkenhuysen, Sviatlana Shashkova et al

Frontiers in Physiology. Vol. 11

Artikel i vetenskaplig tidskrift

2020

Mig1 localization exhibits biphasic behavior which is controlled by both metabolic and regulatory roles of the sugar kinases

Gregor W. Schmidt, Niek Welkenhuysen, Tian Ye et al

Molecular Genetics and Genomics. Vol. 295 (6), p. 1489-1500

Artikel i vetenskaplig tidskrift

2020

The synergy of damage repair and retention promotes rejuvenation and prolongs healthy lifespans in cell lineages

Barbara Maria Schnitzer, Johannes Borgqvist, Marija Cvijovic

PLoS Computational Biology. Vol. 16 (10)

Artikel i vetenskaplig tidskrift

2020

Symmetry structures in dynamic models of biochemical systems

Fredrik Ohlsson, Johannes Borgqvist, Marija Cvijovic

Journal of the Royal Society Interface. Vol. 17 (168)

Artikel i vetenskaplig tidskrift

2019

Cardiac troponin T concentrations and patient-specific risk of myocardial infarction using the novel PALfx parameter

Damiano Ognissanti, Christian Bjurman, Martin J. Holzmann et al

Clinical Biochemistry. Vol. 66, p. 21-28

Artikel i vetenskaplig tidskrift

2019

Adaptive damage retention mechanism enables healthier yeast population

Qasim Ali, Riccardo Dainese, Marija Cvijovic

Journal of Theoretical Biology. Vol. 473, p. 52-66

Artikel i vetenskaplig tidskrift

2019

Challenge model of TNFα turnover at varying LPS and drug provocations

Felix Held, Edmund Hoppe, Marija Cvijovic et al

Journal of Pharmacokinetics and Pharmacodynamics. Vol. 46 (3), p. 223-240

Artikel i vetenskaplig tidskrift

2019

Creating an automated micromanipulator with a microfluidics and optical tweezers approach to study replicative ageing

Niek Welkenhuysen, Martin Mojica-Benavides, Caroline B. Adiels et al

Optical Manipulation and Its Applications - Proceedings Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA, BRAIN, NTM, OMA, OMP)

Paper i proceeding

2019

Modelling of oscillatory cortisol response in horses using a Bayesian population approach for evaluation of dexamethasone suppression test protocols

Felix Held, Carl Ekstrand, Marija Cvijovic et al

Journal of Pharmacokinetics and Pharmacodynamics. Vol. 46 (1), p. 75-87

Artikel i vetenskaplig tidskrift

2019

Robustness of Nutrient Signaling Is Maintained by Interconnectivity Between Signal Transduction Pathways

Niek Welkenhuysen, Barbara Maria Schnitzer, Linnea Österberg et al

Frontiers in Physiology. Vol. 9 (JAN)

Artikel i vetenskaplig tidskrift

2018

Heart rate variability characteristics of patients with irritable bowel syndrome and associations with symptoms

A. Polster, P. Friberg, V. Gunterberg et al

Neurogastroenterology and Motility. Vol. 30 (7)

Artikel i vetenskaplig tidskrift

2018

Bayesian hierarchical model of oscillatory cortisol response during drug intervention

Felix Held, Carl Ekstrand, Edmund Hoppe et al

Poster (konferens)

2018

Focus on resolution

Stefan Hohmann, Marija Cvijovic

Current Opinion in Systems Biology. Vol. 7, p. iv-v

Övrig text i vetenskaplig tidskrift

2017

Integrative analysis of omics data

Tobias Österlund, Marija Cvijovic, Erik Kristiansson

Systems Biology, p. 1-24

Kapitel i bok

2017

Single-cell study links metabolism with nutrient signaling and reveals sources of variability

Niek Welkenhuysen, Johannes Borgqvist, M. Backman et al

BMC Systems Biology. Vol. 11 (1), p. Article Number: 59-

Artikel i vetenskaplig tidskrift

2017

Systems biology of aging

Johannes Borgqvist, Riccardo Dainese, Marija Cvijovic

Systems Biology, p. 262-283

Kapitel i bok

2016

Strategies for structuring interdisciplinary education in systems biology: An European perspective

Marija Cvijovic, Thomas Höfer, Jure Aćimović et al

npj Systems Biology and Applications. Vol. 2

Artikel i vetenskaplig tidskrift

2014

Bridging the gaps in systems biology

Marija Cvijovic, Joachim Almquist, Jonas Hagmar et al

Molecular Genetics and Genomics. Vol. 289 (5), p. 727-734

Reviewartikel

2014

Essential Genetic Interactors of SIR2 Required for Spatial Sequestration and Asymmetrical Inheritance of Protein Aggregates

J. Song, Q. Yang, Junsheng Yang et al

PLoS Genetics. Vol. 10 (7), p. Article Number: e1004539 -

Artikel i vetenskaplig tidskrift

2014

Yeast AMP-activated protein kinase monitors glucose concentration changes and absolute glucose levels

Loubna Bendrioua, Maria Smedh, Joachim Almquist et al

Journal of Biological Chemistry. Vol. 289 (18), p. 12863-12875

Artikel i vetenskaplig tidskrift

2014

Stress granule-defective mutants deregulate stress responsive transcripts

Xiaoxue Yang, Yi Shen, Elena Garré et al

PLoS Genetics. Vol. 10 (11), p. e1004763-

Artikel i vetenskaplig tidskrift

2014

Kinetic models in industrial biotechnology - Improving cell factory performance

Joachim Almquist, Marija Cvijovic, V. Hatzimanikatis et al

Metabolic Engineering. Vol. 24, p. 38-60

Reviewartikel

2013

Removal of damaged proteins during ES cell fate specification requires the proteasome activator PA28

Malin Hernebring, Åsa Fredriksson, M. Liljevald et al

Scientific Reports. Vol. 3 (3), p. artikel nr 1381-

Artikel i vetenskaplig tidskrift

2013

yApoptosis: yeast apoptosis database

Kwanjeera Wanichthanarak, Marija Cvijovic, Andrea Molt et al

Database : the journal of biological databases and curation. Vol. 2013 (Art. no. bat068)

Artikel i vetenskaplig tidskrift

Visa projekt

2012

Does ketoprofen or diclofenac pose the lowest risk to fish?

Filip Cuklev, J. Fick, Marija Cvijovic et al

Journal of Hazardous Materials. Vol. 229-230, p. 100-106

Artikel i vetenskaplig tidskrift

2012

Boolean model of yeast apoptosis as a tool to study yeast and human apoptotic regulations

Laleh Kazemzadeh, Marija Cvijovic, Dina Petranovic Nielsen

Frontiers in Physiology. Vol. 3

Artikel i vetenskaplig tidskrift

2012

Global hepatic gene expression in rainbow trout exposed to sewage effluents: A comparison of different sewage treatment technologies

Filip Cuklev, Lina-Maria Gunnarsson, Marija Cvijovic et al

Science of the Total Environment. Vol. 427-428, p. 106-114

Artikel i vetenskaplig tidskrift

2011

Mathematical models of cell factories: moving towards the core of industrial biotechnology

Marija Cvijovic, Sergio Velasco, Jens B Nielsen

Microbial Biotechnology. Vol. 4 (5), p. 572-584

Artikel i vetenskaplig tidskrift

2010

BioMet Toolbox: genome-wide analysis of metabolism

Marija Cvijovic, Roberto Olivares Hernandez, Rasmus Ågren et al

Nucleic Acids Research. Vol. 38 (SUPPL. 2), p. W144-W149

Artikel i vetenskaplig tidskrift

2008

Selective benefits of damage partitioning in unicellular systems and its effects on aging

Nika Erjavec, Marija Cvijovic, Edda Klipp et al

Proceedings of the National Academy of Sciences of the United States of America. Vol. 105 (48), p. 18764-18769

Artikel i vetenskaplig tidskrift

2007

Identification of putative regulatory upstream ORFs in the yeast genome using heuristics and evolutionary conservation

Marija Cvijovic, Daniel Dalevi, Elizabeth Bilsland et al

BMC Bioinformatics. Vol. 8, p. 295-

Artikel i vetenskaplig tidskrift

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