In vitro evaluation of osteoblastic cells on bacterial cellulose modified with multi-walled carbon nanotubes as scaffold for bone regeneration
Artikel i vetenskaplig tidskrift, 2017

In this paper we explore the use of native bacterial cellulose (BC) in combination with functionalized multi-walled carbon nanotubes (MWNTs) as an original biomaterial, suitable three-dimensional (3D) scaffold for osteoblastic cell culture. Functionalized MWNTs were mixed with native BC (secreted by Gluconacetobacter xylinus) with the aim of reinforcing the mechanical properties of BC. The results indicate that BC-MWNTs scaffolds support osteoblast viability, adhesion and proliferation at higher levels as compared to traditional culture substrates. Chemically functionalized MWNTs are also an excellent material to be used as scaffold because these did not affect cell viability and showed an enhanced osteoblast adhesion. These results suggest the potential for this combination of biomaterials, i.e. BC and carbon nanomaterials, as scaffolds for bone regeneration.

Osteoblastic cells

Bacterial cellulose

Cell adhesion

Functionalized MWNTs

Bone regeneration

Författare

José Manuel Gutiérrez-Hernández

Universidad de Guadalajara

Universidad Autanoma de San Luis Potosí

Diana María Escobar-García

Universidad Polit́cnica de San Luis Potosí

Alfredo Escalante

Universidad de Guadalajara

Hector Flores

Universidad Polit́cnica de San Luis Potosí

Francisco Javier González

Universidad Autanoma de San Luis Potosí

Paul Gatenholm

Chalmers, Kemi och kemiteknik, Tillämpad kemi, Polymerteknologi

Guillermo Toriz Gonzalez

Chalmers, Kemi och kemiteknik, Tillämpad kemi, Polymerteknologi

Materials Science and Engineering C

0928-4931 (ISSN)

Vol. 75 445-453

Drivkrafter

Hållbar utveckling

Styrkeområden

Building Futures

Livsvetenskaper och teknik

Ämneskategorier

Industriell bioteknik

DOI

10.1016/j.msec.2017.02.074

Mer information

Senast uppdaterat

2018-04-04